| Autor: |
Abdel-Aaty HE; Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt., Selim MM, Abdel-Rehim HA |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the Egyptian Society of Parasitology [J Egypt Soc Parasitol] 1999; Vol. 29 (3), pp. 721-34. |
| Abstrakt: |
IFN-gamma, a Th1 cytokine was quantitatively estimated using EASIA in the sera of patients with different stages of schistosomiasis mansoni autoimmune diseases and schistosomal arthropathy. Level of IFN-gamma was significantly elevated in all the test groups compared to the control group. The highest level of IFN-gamma observed was in RA and SLE, with insignificant statistical difference (P > 0.05) between them. Cases with early S. mansoni infection showed significant higher level (P < 0.05) of IFN-gamma compared to hepatosplenic schistosomiasis with and without ascites. A significant statistical difference (P < 0.05) concerning IFN-gamma level was observed when comparing RA and SLE to different stages of S. mansoni infection and schistosomal arthropathy. This might lead to a conclusion that IFN-gamma estimation in sera of patients having joint complaint could be a good marker for differentiation between autoimmune collagen induced arthritis and schistosomiasis induced arthropathy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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