| Autor: |
Xu L; PHLS Antiviral Susceptibility Unit, Division of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK., Hué S, Taylor S, Ratcliffe D, Workman JA, Jackson S, Cane PA, Pillay D |
| Jazyk: |
angličtina |
| Zdroj: |
AIDS (London, England) [AIDS] 2002 Aug 16; Vol. 16 (12), pp. 1684-6. |
| DOI: |
10.1097/00002030-200208160-00016 |
| Abstrakt: |
In-vitro differences in T-20 susceptibility among HIV-1 subtypes have been reported. We therefore studied the T-20 binding domain of a variety of virus subtypes from both antiretroviral-naive and -experienced patients. Minimal variation in the HR-1 region of gp41 was observed, especially within the region responsible for T-20 resistance. Any subtype differences in T-20 susceptibility do not appear to be related to HR-1 genetic variation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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