| Autor: |
DeVane CL; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA. devanel@musc.edu, Grothe DR, Smith SL |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of clinical psychiatry [J Clin Psychiatry] 2002; Vol. 63 Suppl 1, pp. 10-7. |
| Abstrakt: |
The past decade has witnessed the introduction of a diverse group of antidepressants from a variety of distinct chemical classes, each with their own specificity for neurochemical transmitters, receptors, and cytochrome P450 isozymes. This review focuses on nefazodone, a distinct antidepressant with efficacy for the treatment of depression with depression-related anxiety symptoms, an established tolerability profile, and a multimodal mechanism of action. Relevant pharmacologic and pharmacodynamic effects are summarized that support nefazodone as an attractive choice for both the short- and long-term treatment of depression. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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