| Autor: |
Nishio S; Dept. of Obstetrics and Gynecology, Kumamoto Municipal Hospital., Kawata T, Harada C, Kawagoe H, Fujiyoshi K, Ishimatsu J, Tsunawaki A, Sugiyama T, Kamura T |
| Jazyk: |
japonština |
| Zdroj: |
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2002 Feb; Vol. 29 (2), pp. 309-12. |
| Abstrakt: |
We report the use of paclitaxel in the successful treatment of a 74-year-old patient with extraovarian primary peritoneal carcinoma and acute renal failure caused by intraperitoneal cisplatin. The histological diagnosis was papillary serous adenocarcinoma. Paclitaxel was given intravenously at 70 mg/m2 in a 1-hour infusion weekly for 6 consecutive weeks followed by 2-weeks rest (one cycle). Toxicities including neutropenia and neurotoxicity were mild. She showed a clinical response after three cycles, and then underwent secondary cytoreductive surgery after which she received one additional cycle of therapy. She enjoyed a favorable quality of life without evidence of disease for 16 months after the completion of this therapy. Weekly 1-hour paclitaxel (70 mg/m2) was well tolerated, yet was effective for extraovarian primary peritoneal carcinoma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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