[Bone mineral density in patients with rheumatoid arthritis].

Autor: Gukasian DA, Nasonov EL, Balabanova RM, Smirnov AV
Jazyk: ruština
Zdroj: Terapevticheskii arkhiv [Ter Arkh] 2001; Vol. 73 (12), pp. 68-70.
Abstrakt: Aim: To examine the prevalence of osteoporosis (OPO) and osteopenia (OPE) in female patients with rheumatic arthritis (RA).
Material and Methods: 60 female patients with proved diagnosis of RA aged 34-64 years: 30 premenopausal women (median age 41.5 years, disease duration 9.5 years) and 30 postmenopausal women (median age 56.2 years, disease duration 10.2 years). Both groups have not undergone any glucocorticoid or antiosteoporotic therapy. Bone mineral density (BMD) was measured with a Dual Energy X-Ray Absorptiometry (DEXA) in the lumbar spine, proximal segments of the femur, forearm.
Results: In the group of premenopausal patients with RA the rate of OPE was 63% for forearm, 60% for femoral neck, 33% for lumbar spine. In postmenopausal women 53, 50 and 50%, respectively.
Conclusion: Osteoporosis in RA is of a generalized character and can be encountered in peripheral skeleton more often than in the axial one. It is possible to estimate the BMD of one section by means of the BMD indicator of another section.
Databáze: MEDLINE