[Clinical study of anti-leukotriene therapy with montelukast in bronchial asthma patients].

Autor: Tovt-Korshyns'ka MI, Spivak MIa, Chopei IV, Lemko IS, Kopynets' II, Il'ina VO, Kazankevych VP, Melega OO
Jazyk: ukrajinština
Zdroj: Likars'ka sprava [Lik Sprava] 2001 Jul-Aug (4), pp. 157-9.
Abstrakt: Clinical and functional efficacy of the antileukotriene agent montelucast (singulair) was investigated in 30 patients with moderately severe bronchial asthma. Patients with a positive FEV1 response to montelukast (61.1%) demonstrated a higher blood level of IgE and sputum eosinophilia. Enhancement of bronchodilatatory effect secondary to the use of beta 2-agonist has been recordable in the wake of a 24-day montelucast treatment (10 mg o.d.).
Databáze: MEDLINE