Decreased diffusion in central pontine myelinolysis.

Autor: Cramer SC; Department of Neurology, University of Washington, Seattle, WA 98195, USA., Stegbauer KC, Schneider A, Mukai J, Maravilla KR
Jazyk: angličtina
Zdroj: AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 2001 Sep; Vol. 22 (8), pp. 1476-9.
Abstrakt: Two patients with central pontine myelinolysis (CPM) were studied with diffusion-weighted MR imaging 1 week after onset of tetraplegia. In both patients, affected white matter showed hyperintensity on diffusion-weighted images associated with a decrease in apparent diffusion coefficient (ADC) values. In one patient studied serially, ADC values normalized by 3 weeks after tetraplegia. Early in the clinical course, diagnosis of CPM can sometimes be difficult. Hyperintensity on diffusion-weighted images may therefore have diagnostic utility. Decreased lesional ADC values support the notion that CPM is a consequence of relative intracellular hypotonicity.
Databáze: MEDLINE