| Autor: |
Grabchenko NI; Zabolotny Institute of Microbiology and Virology, Kiev, Ukraine., Karpov AV, Chirva VIa, Tkachikova L, Spivak NIa |
| Jazyk: |
ruština |
| Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2001 May-Jun (3), pp. 50-3. |
| Abstrakt: |
The work deals with the results of experimental evaluation of the influence of some new modified derivatives of muramyldipeptide (MDP) on the course of staphylococcal infection in mice. The preparations under study were found to produce rapid elimination of bacteria from kidneys and the increase of phagocytic activity of blood macrophages in animals. At the same time MDP and its derivatives stimulated natural killer cells whose activity was inhibited during infection. The dependence between the structure of these compounds and their protective action in staphylococcal infection, as well as the increase of the natural immunity characteristics of the body was followed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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