Exercise-induced bronchoconstriction among Malay schoolchildren.

Autor: Zainudin NM; Department of Paediatrics, Institut Pediatrik, Hospital Kuala Lumpur, Malaysia. norzila@crc.jaring.my, Aziz BA, Haifa AL, Deng CT, Omar AH
Jazyk: angličtina
Zdroj: Respirology (Carlton, Vic.) [Respirology] 2001 Jun; Vol. 6 (2), pp. 151-5.
DOI: 10.1046/j.1440-1843.2001.00326.x
Abstrakt: Objective: Exercise-induced bronchoconstriction (EIB) may be demonstrated in 60-70% of asthmatic children in temperate climates. In areas of high humidity it is postulated to be low. The aim of the study was to determine the prevalence of EIB in a population of schoolchildren with wheezing, living in the humid tropical climate of Kuala Lumpur, Malaysia.
Method: We performed a cross-sectional study using the International Study of Asthma and Allergies in Childhood questionnaire to identify 7-12-year-old Malay children with asthma symptoms from a primary school in central Kuala Lumpur. Sixty-five of 76 children with 'ever wheeze' performed an exercise challenge test successfully in an uncontrolled environment. A random sample of 80 schoolchildren with no history of wheeze were similarly tested as controls. The relative humidity and temperature were recorded. A fall of > 15% was considered as clinically important.
Results: The prevalence of EIB in schoolchildren with 'ever wheeze' was 47.7%. The prevalence of EIB in children with 'current wheeze' was 51.6%. The prevalence of EIB in controls was 7.5%. The relative humidity during the study ranged from 41 to 90%. There was no significant relationship between different humidity levels and EIB (P = 0.58, regression analysis).
Conclusion: This study demonstrates that EIB is present in asthmatic children despite the highly humid tropical environment.
Databáze: MEDLINE
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