| Autor: |
Bina JE; Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA., Mekalanos JJ |
| Jazyk: |
angličtina |
| Zdroj: |
Infection and immunity [Infect Immun] 2001 Jul; Vol. 69 (7), pp. 4681-5. |
| DOI: |
10.1128/IAI.69.7.4681-4685.2001 |
| Abstrakt: |
TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobial agents, and were deficient in intestinal colonization. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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