In vitro and in vivo characterization of JNJ-31020028 ( N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor

Autor: Shoblock, James R.1 jshobloc@its.jnj.com, Welty, Natalie1, Nepomuceno, Diane1, Lord, Brian1, Aluisio, Leah1, Fraser, Ian1, Motley, S. Timothy1, Sutton, Steve W.1, Morton, Kirsten1, Galici, Ruggero1, Atack, John R.1, Dvorak, Lisa1, Swanson, Devin M.1, Carruthers, Nicholas I.1, Dvorak, Curt1, Lovenberg, Timothy W.1, Bonaventure, Pascal1 pbonave1@its.jnj.com
Zdroj: Psychopharmacology. Feb2010, Vol. 208 Issue 2, p265-277. 13p. 1 Diagram, 3 Charts, 7 Graphs.
Databáze: Academic Search Ultimate