The PARP1 selective inhibitor saruparib (AZD5305) elicits potent and durable antitumor activity in patient-derived BRCA1/2-associated cancer models.

Autor: Herencia-Ropero, Andrea1,2 (AUTHOR), Llop-Guevara, Alba1 (AUTHOR) alballop@gmail.com, Staniszewska, Anna D.3 (AUTHOR), Domènech-Vivó, Joanna4,5 (AUTHOR), García-Galea, Eduardo6 (AUTHOR), Moles-Fernández, Alejandro7,8 (AUTHOR), Pedretti, Flaminia1 (AUTHOR), Domènech, Heura1 (AUTHOR), Rodríguez, Olga1 (AUTHOR), Guzmán, Marta1 (AUTHOR), Arenas, Enrique J.9,10,11 (AUTHOR), Verdaguer, Helena12,13 (AUTHOR), Calero-Nieto, Fernando J.3 (AUTHOR), Talbot, Sara3 (AUTHOR), Tobalina, Luis3 (AUTHOR), Leo, Elisabetta3 (AUTHOR), Lau, Alan3 (AUTHOR), Nuciforo, Paolo14 (AUTHOR), Dienstmann, Rodrigo6 (AUTHOR), Macarulla, Teresa12,13 (AUTHOR)
Zdroj: Genome Medicine. 8/26/2024, Vol. 16 Issue 1, p1-17. 17p.
Databáze: Academic Search Ultimate
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