The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta.

Autor: Chae, Sehyun1 (AUTHOR), Lee, Hyun-ju2 (AUTHOR), Lee, Ha-Eun3 (AUTHOR), Kim, Jieun2 (AUTHOR), Jeong, Yoo Joo2,4 (AUTHOR), Lin, Yuxi5 (AUTHOR), Kim, Hye Yun3 (AUTHOR), Leriche, Geoffray6 (AUTHOR), Ehrlich, Rachel S.6 (AUTHOR), Lingl, Sascha Castro6 (AUTHOR), Seo, Min-Duk7 (AUTHOR), Lee, Young-Ho5,8,9 (AUTHOR), Yang, Jerry6 (AUTHOR) jerryyang@ucsd.edu, Kim, Jae-Ick3 (AUTHOR) jikim220@unist.ac.kr, Hoe, Hyang-Sook2,4,10 (AUTHOR) sookhoe72@kbri.re.kr
Zdroj: Journal of Neuroinflammation. 8/11/2024, Vol. 21 Issue 1, p1-34. 34p.
Databáze: Academic Search Ultimate
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