The mutation Y1206S increases the affinity of the sulphonylurea receptor SUR2A for glibenclamide and enhances the effects of coexpression with Kir6.2.

Autor: Stephan, Damian1, Stauß, Eva1, Lange, Ulf1, Felsch, Holger1, Löffler-Walz, Cornelia1, Hambrock, Annette1, Russ, Ulrich1, Quast, Ulrich1 ulrich.quast@uni-tuebingen.de, Stauss, Eva (AUTHOR), Löffler-Walz, Cornelia (AUTHOR)
Zdroj: British Journal of Pharmacology. Apr2005, Vol. 144 Issue 8, p1078-1088. 11p.
Databáze: Academic Search Ultimate