The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influx.

Autor: Tian Wang1, Reingruber, Jü rgen2, Woodruff, Michael L.3, Majumder, Anurima4, Camarena, Andres1, Artemyev, Nikolai O.5, Fain, Gordon L.1, Jeannie Chen2 jeannie@usc.edu
Zdroj: Journal of Biological Chemistry. 10/5/2018, Vol. 293 Issue 40, p15332-15346. 15p.
Databáze: Academic Search Ultimate