Zobrazeno 1 - 10
of 2 952
pro vyhledávání: '"zo-1"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Increasing evidence supports the crucial role of Epithelial-Mesenchymal Transition (EMT) in cancer invasion and metastasis. N-acetylglucosaminyltransferase V (MGAT5), which is associated with multiantenna glycosylation, can contribute to tum
Externí odkaz:
https://doaj.org/article/1052e5a1e7ed430ab14abf9117671949
Publikováno v:
Journal of Future Foods, Vol 5, Iss 1, Pp 68-78 (2025)
Methionine (Met) restriction in the diet can reduce intestinal permeability by modulating the expression of intestinal tight proteins leading to enhance the integrity of the intestinal epithelium. Furthermore, our previous study observed that 2-hydro
Externí odkaz:
https://doaj.org/article/9b24666d55a94613a4f80cd324d710f1
Autor:
Zhicheng Wei, Hangdong Shen, Fan Wang, Weijun Huang, Xinyi Li, Huajun Xu, Huaming Zhu, Jian Guan
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Intestinal barrier dysfunction and systemic inflammation are common in obstructive sleep apnoea (OSA). We aimed to investigate the role of melatonin, an anti-inflammatory mediator, in mediating the relationships between OSA, intestinal bar
Externí odkaz:
https://doaj.org/article/6f7d461ea7774b31b25b6c257a3f6c3c
Autor:
Lorenzo Zavagna, Eligio F. Canelli, Bahareh Azimi, Fabiola Troisi, Lorenzo Scarpelli, Teresa Macchi, Giuseppe Gallone, Massimiliano Labardi, Roberto Giovannoni, Mario Milazzo, Serena Danti
Publikováno v:
Macromolecular Materials and Engineering, Vol 309, Iss 10, Pp n/a-n/a (2024)
Abstract Recently, in vitro models emerge as valuable tools in biomedical research by enabling the investigation of complex physiological processes in a controlled environment, replicating some traits of interest of the biological tissues. This study
Externí odkaz:
https://doaj.org/article/dfe743c748ac415fac29a9ccd25a26f4
Autor:
Hyun-Chae Lee, Sun-Hee Park, Hye Min Jeong, Goeun Shin, Sung In Lim, Jeongtae Kim, Jaewon Shim, Yeong-Min Park, Kyoung Seob Song
Publikováno v:
eLife, Vol 13 (2024)
The gram-negative bacterium lipopolysaccharide (LPS) is frequently administered to generate models of systemic inflammation. However, there are several side effects and no effective treatment for LPS-induced systemic inflammation. PEGylated PDZ pepti
Externí odkaz:
https://doaj.org/article/4b911912fecd4b64a8b073bd6f02370f
Autor:
Mototsugu Watanabe, Hiroko Nakai, Tatsuya Ohara, Kengo Kawasaki, Shinji Murosaki, Yoshitaka Hirose
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Heat-killed Lactiplantibacillus plantarum L-137 (HK L-137) has been suggested to enhance the intestinal barrier in obese mice, leading to improvement of metabolic abnormalities and adipose tissue inflammation, and in healthy humans with over
Externí odkaz:
https://doaj.org/article/e261d26a1bcf4eafa9b14534efe5d2ba
Autor:
Ruijie Li, Yilin Liu, Jihao Wu, Xiong Chen, Qiying Lu, Kai Xia, Congyuan Liu, Xin Sui, Yixuan Liu, Yiling Wang, Yuan Qiu, Jinsi Chen, Yi Wang, Ruijun Li, Yucheng Ba, Jiayun Fang, Weijun Huang, Zhengqi Lu, Yanbing Li, Xinxue Liao, Andy Peng Xiang, Yinong Huang
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract Adaptive metabolic responses and innate metabolites hold promising therapeutic potential for stroke, while targeted interventions require a thorough understanding of underlying mechanisms. Adiposity is a noted modifiable metabolic risk facto
Externí odkaz:
https://doaj.org/article/b3c69e54927445ea94b421e272b3696e
Autor:
V. L. Bilous, A. O. Tykhomyrov
Publikováno v:
The Ukrainian Biochemical Journal, Vol 96, Iss 1, Pp 37-48 (2024)
Prolonged inflammation and excessive neovascularization of the cornea due to severe injury can impair optical clarity and lead to vision impairment. Plasminogen kringle (K) fragments, known as angiostatins (AS), play a well-established role as inhibi
Externí odkaz:
https://doaj.org/article/ac8aac13fad1452088611d36ce59649d
Publikováno v:
Polish Journal of Pathology, Vol 74, Iss 4, Pp 248-255 (2024)
Thyroid neoplasms are the most common endocrine malignancies. ZIP4 is an intramembranous zinc trans membrane protein. Zinc plays a central role in the activation of transcription factors, and zinc transporters. This affects tumour migration, invasion
Externí odkaz:
https://doaj.org/article/d8b1225160274554af5e02229850b87a
Autor:
Irshad Sharafutdinov, Aileen Harrer, Mathias Müsken, Klemens Rottner, Heinrich Sticht, Christian Täger, Michael Naumann, Nicole Tegtmeyer, Steffen Backert
Publikováno v:
Cell Insight, Vol 3, Iss 3, Pp 100161- (2024)
Cell polarity is crucial for gastric mucosal barrier integrity and mainly regulated by polarity-regulating kinase partitioning-defective 1b (Par1b). During infection, the carcinogen Helicobacter pylori hijacks Par1b via the bacterial oncoprotein CagA
Externí odkaz:
https://doaj.org/article/7a045f07d3ac43e7910e40795eeae52e