Zobrazeno 1 - 10
of 81
pro vyhledávání: '"zinc-finger nucleases (ZFNs)"'
Autor:
Xiaofeng Dai, Pilar Blancafort, Peiyu Wang, Agustin Sgro, Erik W. Thompson, Kostya (Ken) Ostrikov
Publikováno v:
Advanced Science, Vol 7, Iss 12, Pp n/a-n/a (2020)
Abstract The development of clustered regularly interspaced short palindromic repeats (CRISPR) has spurred a successive wave of genome‐engineering following zinc finger nucleases and transcription activator‐like effector nucleases, and made gene
Externí odkaz:
https://doaj.org/article/8f22ee66481f4b4f94ade555fc0522a2
Over the past decade, the CRISPR-based genome editing technology has made a transformative impact on basic and applied biological research, revolutionizing various fields including medicine and agriculture. This survey paper provides a comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02060b9f3b44530f674094268589bfe5
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Genome editing technologies enable precise modifications of DNA sequences in vivo and offer a great promise for harnessing plant genes in crop improvement. The precise manipulation of plant genomes relies on the induction of DNA double-strand breaks
Externí odkaz:
https://doaj.org/article/829d8c6e772240ce99ca68c67a103e23
Autor:
Christian eCantos, Perigio eFransisco, Kurniawan Rudi Trijatmiko, Inez eSlamet-Loedin, Prabhjit Kaur Chadha-Mohanty
Publikováno v:
Frontiers in Plant Science, Vol 5 (2014)
Zinc-finger nucleases (ZFNs) have proved to be successful tools for targeted genome manipulation in several organisms. Their main property is the induction of double-strand breaks (DSBs) at specific sites, which are further repaired through homologou
Externí odkaz:
https://doaj.org/article/ad33b1ad56b941da82e48da7f90f3b91
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Cell Transplantation
Cell Transplantation
In this review, we introduce current developments in induced pluripotent stem cells (iPSCs), site-specific nuclease (SSN)-mediated genome editing tools, and the combined application of these two novel technologies in biomedical research and therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293c0eeeb252f2af79caf71b47c89a08
https://doi.org/10.1177/0963689718754560
https://doi.org/10.1177/0963689718754560
Akademický článek
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Publikováno v:
Journal of Molecular Biology. 428:963-989
Genome engineering with programmable nucleases depends on cellular responses to a targeted double-strand break (DSB). The first truly targetable reagents were the zinc finger nucleases (ZFNs) that showed that arbitrary DNA sequences could be addresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c20ebb5115010b7d2bd2da4150e978
https://doi.org/10.1016/j.jmb.2015.10.014
https://doi.org/10.1016/j.jmb.2015.10.014
Publikováno v:
Advanced Science, Vol 7, Iss 12, Pp n/a-n/a (2020)
Advanced Science
Advanced Science
The development of clustered regularly interspaced short palindromic repeats (CRISPR) has spurred a successive wave of genome‐engineering following zinc finger nucleases and transcription activator‐like effector nucleases, and made gene‐editing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bae9a486fd52622bff009137a5925b
https://doi.org/10.1002/advs.201902552
https://doi.org/10.1002/advs.201902552
Autor:
Yih-Jing Lee, Hueng-Chuen Fan, Shinn Zong Lin, Jeng Dau Tsai, Horng-Jyh Harn, Ching Shiang Chi
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 27 (2018)
Cell Transplantation, Vol 27 (2018)
Neurodegenerative diseases (NDs), at least including Alzheimer’s, Huntington’s, and Parkinson’s diseases, have become the most dreaded maladies because there are no precise diagnostic tools or definite treatments for these debilitating diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c27da03c80d7f93c0fbce20b644432
https://pubmed.ncbi.nlm.nih.gov/29766738
https://pubmed.ncbi.nlm.nih.gov/29766738
Akademický článek
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