Zobrazeno 1 - 10
of 1 188
pro vyhledávání: '"zebrafish model"'
Autor:
Yong-Ren Chen, Chin-Chean Wong, Yi-No Chen, Bing-Heng Yang, Po-Hui Lee, Chia-Yang Shiau, Kuo-Chuan Wang, Chung-Hsing Li
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 4, Pp 2035-2044 (2024)
Background/purpose: Mesenchymal stem cells exhibit therapeutic efficacy for brain injury. This study examined the effect of mesenchymal stem cells derived from human exfoliated deciduous teeth (SHED) on alleviating symptoms of Parkinson's disease (PD
Externí odkaz:
https://doaj.org/article/422b98c97f514ddf8071a3746c81f24a
Autor:
Sissy Bassani, Jacqueline Chrast, Giovanna Ambrosini, Norine Voisin, Frédéric Schütz, Alfredo Brusco, Fabio Sirchia, Lydia Turban, Susanna Schubert, Rami Abou Jamra, Jan-Ulrich Schlump, Desiree DeMille, Pinar Bayrak-Toydemir, Gary Rex Nelson, Kristen Nicole Wong, Laura Duncan, Mackenzie Mosera, Christian Gilissen, Lisenka E. L. M. Vissers, Rolph Pfundt, Rogier Kersseboom, Hilde Yttervik, Geir Åsmund Myge Hansen, Marie Falkenberg Smeland, Kameryn M. Butler, Michael J. Lyons, Claudia M. B. Carvalho, Chaofan Zhang, James R. Lupski, Lorraine Potocki, Leticia Flores-Gallegos, Rodrigo Morales-Toquero, Florence Petit, Binnaz Yalcin, Annabelle Tuttle, Houda Zghal Elloumi, Lane McCormick, Mary Kukolich, Oliver Klaas, Judit Horvath, Marcello Scala, Michele Iacomino, Francesca Operto, Federico Zara, Karin Writzl, Aleš Maver, Maria K. Haanpää, Pia Pohjola, Harri Arikka, Anneke J. A. Kievit, Camilla Calandrini, Christian Iseli, Nicolas Guex, Alexandre Reymond
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background We previously described the KINSSHIP syndrome, an autosomal dominant disorder associated with intellectual disability (ID), mesomelic dysplasia and horseshoe kidney, caused by de novo variants in the degron of AFF3. Mouse knock-in
Externí odkaz:
https://doaj.org/article/0358fc56f6054b188a138c71c996e968
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 2, Pp 136-144 (2024)
Abstract Background Despite the success of tyrosine kinase inhibitors in chronic myeloid leukemia (CML) therapy, CML still faces the challenges of drug resistance and progression to blast crisis. Twenty‐five percent of patients have imatinib resist
Externí odkaz:
https://doaj.org/article/1eb1d8a4412d4f64b4f807567b2d3c11
Autor:
Jing-Lan Ni, Hua-Ming Wen, Xiao-Sheng Huang, Qian-Wen Li, Jia-Min Cai, Bao-Jian Fan, Jun Zhao
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 3, Pp 454-465 (2024)
AIM: To identify disease-causative mutations in families with congenital cataract. METHODS: Two Chinese families with autosomal-dominant congenital cataract (ADCC) were recruited and underwent comprehensive eye examinations. Gene panel next-generatio
Externí odkaz:
https://doaj.org/article/5556a235b19246048a61a3c3eb41a3fd
Autor:
Dianlong Kang, Yucheng Yang, Yibo Zhang, Jianbin Zhang, Qianyi He, Zhihuo Luo, An Hong, Yong Wang, Xujing Liang, Jing Chen, Xiaojia Chen
Publikováno v:
Journal of Functional Foods, Vol 121, Iss , Pp 106373- (2024)
The escalating prevalence of non-alcoholic fatty liver disease (NAFLD), driven by inadequate dietary habits and metabolic imbalances, underscores the urgent need for effective dietary interventions. This study investigated the potential of 80 % peanu
Externí odkaz:
https://doaj.org/article/4aa2e587567a426d94e284f0785bad52
Autor:
Giulia Abate, Alex Pezzotta, Mariachiara Pucci, Valeria Bortolotto, Giovanni Ribaudo, Sara A. Bonini, Andrea Mastinu, Giuseppina Maccarinelli, Alberto Ongaro, Emanuela Tirelli, Daniela Zizioli, Alessandra Gianoncelli, Maurizio Memo, Mariagrazia Grilli, Daniela Uberti
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 969 (2024)
Gamma-oryzanol (ORY), found in rice (Oryza sativa L.), is a mixture of ferulic acid esters with triterpene alcohols, well-known for its antioxidant and anti-inflammatory properties. Our past research demonstrated its positive impact on cognitive func
Externí odkaz:
https://doaj.org/article/29276847e45a4cd58f177918e136ae7b
Autor:
Vincenza De Gregorio, Alessandra La Pietra, Andrea Candela, Carlo Oliviero, Ida Ferrandino, Diego Tesauro
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100174- (2024)
Gold complexes can be a useful system in the fight against cancer. Although many studies have been carried out on in vitro 2D cell culture models embryotoxic assays are particularly lacking. Embryotoxicity and DNA damage are critical concerns in drug
Externí odkaz:
https://doaj.org/article/1dda750de81b4c76878c74082d578715
Autor:
Dixuan Yang, Zhenjie Jian, Changfa Tang, Zhanglin Chen, Zuoqiong Zhou, Lan Zheng, Xiyang Peng
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5943 (2024)
Congenital heart defects (CHDs) are common human birth defects. Genetic mutations potentially cause the exhibition of various pathological phenotypes associated with CHDs, occurring alone or as part of certain syndromes. Zebrafish, a model organism w
Externí odkaz:
https://doaj.org/article/be48d6e78f4049dd875b1bbbb4c0a40f
Autor:
Ruiya Yi, Bo Yang, Hongjie Zhu, Yu Sun, Hailan Wu, Zhihao Wang, Yongbo Lu, Ya-Wen He, Jing Tian
Publikováno v:
Nutrients, Vol 16, Iss 11, p 1562 (2024)
The imbalance of gut microbiota is an important factor leading to inflammatory bowel disease (IBD). Diffusible signal factor (DSF) is a novel quorum-sensing signal that regulates bacterial growth, metabolism, pathogenicity, and host immune response.
Externí odkaz:
https://doaj.org/article/56e2d75391b34813badde28df17ba8c3
Publikováno v:
Shipin Kexue, Vol 44, Iss 11, Pp 134-142 (2023)
In order to investigate the molecular mechanism behind the anti-inflammatory effect of Camellia fascicularis polyphenols (CFP), the anti-inflammatory activity of CFP was evaluated using the zebrafish model and the polyphenol composition was analyzed
Externí odkaz:
https://doaj.org/article/37669d90fee3483c871fbd5e190897e3