Zobrazeno 1 - 3
of 3
pro vyhledávání: '"zaviralci MurA"'
Autor:
Macarena Funes Chabán, Martina Hrast, Rok Frlan, Dafni G. Graikioti, Constantinos M. Athanassopoulos, María Cecilia Carpinella
Publikováno v:
Antibiotics, Vol 10, Iss 1535, p 1535 (2021)
Antibiotics, vol. 10, no. 12, 1535, 2021.
Antibiotics; Volume 10; Issue 12; Pages: 1535
Antibiotics, vol. 10, no. 12, 1535, 2021.
Antibiotics; Volume 10; Issue 12; Pages: 1535
Enzymes MurA and MurF, involved in bacterial cell wall synthesis, have been validated as targets for the discovery of novel antibiotics. A panel of plant-origin antibacterial diterpenes and synthetic analogs derived therefrom were investigated for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70f8bebf6ff9330f2eeeac097c40839
https://www.mdpi.com/2079-6382/10/12/1535
https://www.mdpi.com/2079-6382/10/12/1535
Autor:
Faganelj, Meta
Pojav in širjenje bakterijskih sevov, odpornih na protibakterijske učinkovine, predstavlja velik zdravstveni problem na svetovni ravni, zato je vedno večja potreba po odkrivanju novih zdravil. Med najbolj znane tarče pri iskanju novih protibakter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3505::7b2e4c6301b01776cc0101c1e596f52b
https://hdl.handle.net/20.500.12556/RUL-121704
https://hdl.handle.net/20.500.12556/RUL-121704
Autor:
Stanislav Gobec, Péter Ábrányi-Balogh, Iwan J. P. de Esch, László Petri, Martina Hrast, Aaron Keeley, David J. Hamilton, György M. Keserű, Maikel Wijtmans, Tímea Imre
Publikováno v:
Pharmaceuticals, vol. 13, no. 11, 362, 2020.
Pharmaceuticals, 13(11):362, 1-14. Multidisciplinary Digital Publishing Institute (MDPI)
Hamilton, D J, Ábrányi-Balogh, P, Keeley, A, Petri, L, Hrast, M, Imre, T, Wijtmans, M, Gobec, S, de Esch, I J P & Keserű, G M 2020, ' Bromo-cyclobutenaminones as new covalent udp-n-acetylglucosamine enolpyruvyl transferase (Mura) inhibitors ', Pharmaceuticals, vol. 13, no. 11, 362, pp. 1-14 . https://doi.org/10.3390/ph13110362
Pharmaceuticals, Vol 13, Iss 362, p 362 (2020)
Pharmaceuticals, 13(11):362, 1-14. Multidisciplinary Digital Publishing Institute (MDPI)
Hamilton, D J, Ábrányi-Balogh, P, Keeley, A, Petri, L, Hrast, M, Imre, T, Wijtmans, M, Gobec, S, de Esch, I J P & Keserű, G M 2020, ' Bromo-cyclobutenaminones as new covalent udp-n-acetylglucosamine enolpyruvyl transferase (Mura) inhibitors ', Pharmaceuticals, vol. 13, no. 11, 362, pp. 1-14 . https://doi.org/10.3390/ph13110362
Pharmaceuticals, Vol 13, Iss 362, p 362 (2020)
Drug discovery programs against the antibacterial target UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) have already resulted in covalent inhibitors having small three- and five-membered heterocyclic rings. In the current study, the reactivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd3ef395cfbf8d8b219e2d8e2f45204
https://doi.org/10.3390/ph13110362
https://doi.org/10.3390/ph13110362