Zobrazeno 1 - 10
of 52
pro vyhledávání: '"xiao rui Cheng"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
IntroductionAlzheimer’s disease is the most common form of dementia and closely related to aging. Qi-Fu-Yin is widely used to treat dementia, but its anti-aging effects is unknown.MethodsWe used 11-month-old APP/PS1 transgenic mice for behavioral t
Externí odkaz:
https://doaj.org/article/a2942f7f882644668cdf7e92ae79f1fd
Autor:
Jin-Wu Zhou, Chu-Tse Wu, Xiao-Rui Cheng, Tong-Xing Wang, Wen-Xia Zhou, Liangren Zhang, Zhenming Liu, Xiao-Yan Zhang, Man Zhao, Wen-Liang Rang
Publikováno v:
Journal of Alzheimer's Disease. 81:981-1038
Background: The toxicity of excessive glutamate release has been implicated in various acute and chronic neurodegenerative conditions. Vesicular glutamate transporters (VGLUTs) are the major mediators for the uptake of glutamate into synaptic vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1979da5f7444c8d9c3082a277255dc5d
https://doi.org/10.3233/jad-210117
https://doi.org/10.3233/jad-210117
Background Anxiety disorder is a common mental disorder. It is necessary to establish a rapid, stable and specific anxiety model to provide theoretical basis for further research on the pathogenesis of anxiety and drug development. Aim Establish a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b699b7f5dc8d7b92175d93fd79e7dda
https://doi.org/10.21203/rs.3.rs-731767/v1
https://doi.org/10.21203/rs.3.rs-731767/v1
Publikováno v:
Chinese Journal of Natural Medicines. 17:103-121
Liu-Wei-Di-Huang (LW) is a Yin nourishing and kidney tonifying prescription in traditional Chinese medicine with promising pharmacological characteristics that can be further exploited and developed in modern medicine. We provide a comprehensive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd9bf40acfdb88d51862173036ac2d1
https://doi.org/10.1016/s1875-5364(19)30013-5
https://doi.org/10.1016/s1875-5364(19)30013-5
LW-AFC is a new formula derived from the Liuwei Dihuang decoction, a classical traditional Chinese medicine prescription. Based on our research, LW-AFC is a promising drug for Alzheimer's disease (AD). The studies were conducted primarily in two typi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17587a9dac64e7a9720185fc662e9b3
https://doi.org/10.1016/bs.apha.2019.10.005
https://doi.org/10.1016/bs.apha.2019.10.005
Autor:
Yong-Xiang Zhang, Xiao-Rui Cheng, Ju Zeng, Jianhui Wang, Wen-Xia Zhou, Xiaorui Zhang, Shanyi Qiao, Jun-Ping Cheng, Feng Liu, Yiran Xu
Publikováno v:
Current Alzheimer Research. 14:221-238
Background: Alzheimer’s disease (AD), the most common cause of dementia among older people, could not be prevented, halted, or reversed up till now. A large body of pharmacological study has revealed that Liuwei Dihuang decoction (LW), a classical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb908046cd7afdc56108fa7d7eb3a673
https://doi.org/10.2174/1567205013666160603001637
https://doi.org/10.2174/1567205013666160603001637
Autor:
Xiao-Rui Cheng, Yang Yu, Xin-Sheng Yao, Wei-Yang Zhang, Wen-Xia Zhou, Xiao-Lin Feng, Da-Peng Qin, Hao Gao
Publikováno v:
RSC Advances. 7:8512-8520
A novel 7-O-7′ type mesomeric neolignan, meso-asarolignan A (1), six pairs of new neolignan enantiomers, (±)-asarolignan B–G (2a/2b, 3a/3b, 4–6, 7a/7b), along with 16 known analogues (8–23) were isolated from the rhizomes of Acorus tatarinow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2570350b27e27261a92d38a19da4e888
https://doi.org/10.1039/c6ra27786a
https://doi.org/10.1039/c6ra27786a
Design and synthesis of 5-cyclopropyl substituted cyclic acylguanidine compounds as BACE1 inhibitors
Publikováno v:
Chinese Chemical Letters. 27:1626-1629
By taking compound 1 as a lead, a series of 5-cyclopropyl substituted cyclic acylguanidine compounds were designed and synthesized as BACE1 inhibitors, compound 4d exhibited 84-fold improved inhibition efficiency than lead compound 1. The diphenyl fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ba4a117de57a395e476402de78666b
https://doi.org/10.1016/j.cclet.2016.05.002
https://doi.org/10.1016/j.cclet.2016.05.002
Autor:
Jun-Ping Cheng, Wenxia Zhou, Jianhui Wang, Yiran Xu, Xiaorui Zhang, Ju Zeng, Yongxiang Zhang, Xiao-Rui Cheng
Publikováno v:
Oncotarget
Although there were considerable advances in the anti-aging medical field, it is short of therapeutic drug for anti-aging. Mounting evidence indicates that the immunosenescence is the key physiopathological mechanism of aging. This study showed the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c2e999d12c7cd9e5b65d81aac26e77
http://europepmc.org/articles/PMC5053624
http://europepmc.org/articles/PMC5053624
Autor:
Shengqi Wang, Tongxing Wang, Jianhui Wang, Jun-Ping Cheng, Wenxia Zhou, Fei Li, Xiaorui Zhang, Xiao-Rui Cheng, Yongxiang Zhang, Feng Liu, Bo Xiaochen, Wenjian Xu
Publikováno v:
Oncotarget
// Jian-hui Wang 1,2,* , Xiao-rui Cheng 1,2,* , Xiao-rui Zhang 1,2 , Tong-xing Wang 1,2 , Wen-jian Xu 3 , Fei Li 3 , Feng Liu 1,2 , Jun-ping Cheng 1,2 , Xiao-chen Bo 3 , Sheng-qi Wang 3 , Wen-xia Zhou 1,2 and Yong-xiang Zhang 1,2 1 Department of Neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc72a7563e4ccd1c998ed18e0436518
https://doi.org/10.18632/oncotarget.8453
https://doi.org/10.18632/oncotarget.8453