Zobrazeno 1 - 10
of 378
pro vyhledávání: '"x-linked thrombocytopenia"'
Autor:
Serena Hamanaka, MD, Toru Uchiyama, MD, PhD, Tadashi Kaname, MD, PhD, Motohiro Matsui, MD, Hiroshi Yoshihashi, MD, Atsushi Makimoto, MD, PhD, Yuki Yuza, MD, Akira Ishiguro, MD
Publikováno v:
Journal of Pediatrics: Clinical Practice, Vol 14, Iss , Pp 200128- (2024)
We present a case of X-linked thrombocytopenia (XLT) with a novel WAS gene variant expressing a normal amount of Wiskott-Aldrich syndrome protein (WASp) in lymphocytes. XLT usually decreases WASp expression not only in platelets, but also in lymphocy
Externí odkaz:
https://doaj.org/article/3dafd6dba22f46859e9e68ef6f1112e6
Autor:
Saori Katayama, Tomohiro Nakano, Tasuku Suzuki, Masahiro Irie, Hidetaka Niizuma, Atsuo Kikuchi, Yoji Sasahara
Publikováno v:
Clinical Immunology Communications, Vol 5, Iss , Pp 34-40 (2024)
Immunological dysfunction in multiple lineages of hematopoietic cells and mixed chimerism after allogeneic hematopoietic stem cell transplantation (HSCT) are associated with an increased risk of autoimmunity in patients with Wiskott-Aldrich syndrome
Externí odkaz:
https://doaj.org/article/54f750006e8e4850a2d186c9647397df
Akademický článek
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Autor:
Natsumon Udomkittivorakul, Duangrurdee Wattanasirichaigoon, Wiparat Manuyakorn, Pongpak Pongphitcha, Arthaporn Khongkraparn, Padcha Tunlayadechanont, Nongnuch Sirachainan
Publikováno v:
Platelets, Vol 33, Iss 5, Pp 792-796 (2022)
Wiskott-Aldrich syndrome (WAS)/X-linked thrombocytopenia (XLT) is a rare X-linked disease characterized by thrombocytopenia, eczema, and recurrent infection. In addition, WAS/XLT increases incidence of autoimmune diseases and malignancies. We reporte
Externí odkaz:
https://doaj.org/article/e332b4310dca485ca623f0ea5e408804
Publikováno v:
Journal of Multidisciplinary Healthcare, Vol Volume 14, Pp 3497-3512 (2021)
Smitha Hosahalli Vasanna, Maria A Pereda, Jignesh Dalal Department of Pediatrics, Division of Pediatric Hematology Oncology, Rainbow Babies and Children’s Hospital, University Hospitals, Cleveland, OH, USACorrespondence: Jignesh DalalDepartment of
Externí odkaz:
https://doaj.org/article/c477d2eeaf46461a83761c7aa0103a0a
Publikováno v:
Journal of Pediatric and Neonatal Individualized Medicine, Vol 12, Iss 1, Pp e120105-e120105 (2022)
Wiskott-Aldrich syndrome (WAS), X-linked thrombocytopenia, and X-linked congenital neutropenia collectively are designated WAS-related disorders. All are attributable to pathogenic variants of the WAS protein (WASp) and present a broad spectrum of he
Externí odkaz:
https://doaj.org/article/f05ca9294c574446ae8b1edef69c0eac
Publikováno v:
Journal of Blood Medicine, Vol Volume 12, Pp 435-447 (2021)
Kanwaldeep K Mallhi,1– 3 Aleksandra Petrovic,1,2,4,* Hans D Ochs2,5,* 1Fred Hutchinson Cancer Research Center, Seattle, WA, USA; 2Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA; 3Division of Hematology and O
Externí odkaz:
https://doaj.org/article/ce6f91bee47e4118ae45bd12eccc3a26
Publikováno v:
One Health & Risk Management, Vol 2, Iss 3, Pp 61-66 (2021)
Introduction. Wiskott-Aldrich syndrome is a rare X-linked disorder characterized by microthrombocytopenia, eczema, and recurrent infections. It is caused by mutations of the WAS gene which encodes the WAS protein (WASp) – a key regulator of actin p
Externí odkaz:
https://doaj.org/article/7a8d87db532b4782af038dc2d666bd34
Akademický článek
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Autor:
Deepti Suri, Rashmi Rikhi, Ankur K. Jindal, Amit Rawat, Murugan Sudhakar, Pandiarajan Vignesh, Anju Gupta, Anit Kaur, Jyoti Sharma, Jasmina Ahluwalia, Prateek Bhatia, Alka Khadwal, Revathi Raj, Ramya Uppuluri, Mukesh Desai, Prasad Taur, Ambreen A. Pandrowala, Vijaya Gowri, Manisha R. Madkaikar, Harsha Prasada Lashkari, Sagar Bhattad, Harish Kumar, Sanjeev Verma, Kohsuke Imai, Shigeaki Nonoyama, Osamu Ohara, Koon W. Chan, Pamela P. Lee, Yu Lung Lau, Surjit Singh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundWiskott Aldrich syndrome (WAS) is characterized by bleeding manifestations, recurrent infections, eczema, autoimmunity, and malignancy. Over the last decade, improved awareness and better in-house diagnostic facilities at several centers in
Externí odkaz:
https://doaj.org/article/40f9e91155324dac9955f31d9057e303