Changing Incidence of Invasive Pneumococcal Disease in Infants Less Than 90 Days of Age Before and After Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Blantyre, Malawi: A 14-Year Hospital Based Surveillance Study

Autor: Marianne Koenraads, Todd D. Swarthout, Naor Bar-Zeev, Comfort Brown, Jacquline Msefula, Brigitte Denis, Queen Dube, Stephen B. Gordon, Robert S. Heyderman, Melissa J. Gladstone, Neil French

Publikováno v: PEDIATRIC INFECTIOUS DISEASE JOURNAL

Background: \ud \ud Invasive pneumococcal disease (IPD) in young infants is uncommon but associated with high morbidity and mortality. Accurate data on the burden of IPD in young infants in low-income countries are lacking. We examined the burden of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462618bf08fc41b1e88a6698ecde921e
https://pubmed.ncbi.nlm.nih.gov/35703302

PRObiotics and SYNbiotics to improve gut health and growth in infants in western Kenya (PROSYNK Trial): Study protocol for a 4-arm, open-label, randomised,\ud controlled trial

Autor: Otiti, Mary, Kariuki, Simon, Wang, Duolao, Hall, Lindsay J, terKuile, Feiko, Allen, Stephen

Background\ud Malnutrition amongst under-fives remains common in resource-poor countries and is resistant to current interventions. New opportunities have emerged to target “environmental enteric dysfunction” (EED) that refers to the abnormal gut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::91bea23dbf813e91e1c5cfd85f1f1b58
https://archive.lstmed.ac.uk/20185/1/Trials_23_284.pdf

The Aetiology of pneumonia from analysis of Lung aspirate and Pleural fluid samples: Findings from the PERCH study

Autor: Ebruke, Bernard E, Knoll, Maria Deloria, Haddix, Meredith, Akramuzzaman, SyedMohd, Prosperi, Christine, Feikin, Daniel R, Hammitt, Laura L, Levine, Orin S, O'Brien, Katherine L, R Murdoch, David, Brooks, W Abdullah, Scott, J Anthony G, Kotloff, Karen L, Madhi, Shabir A, Thea, Donald M, Baillie, Vicky L, Chisti, Mohammod Jobayer, Dione, Michel, J Driscoll, Amanda, Fancourt, Nicholas, Karron, Ruth A, Le, Tham T, Mohamed, Shebe, Moore, David P, C Morpeth, Susan, Mwaba, John, Mwansa, James, Shahid, Abu Sadat Mohammad Sayeem Bin, Sow, Samba O, Tapia, Milagritos D, Antonio, Martin, Howie, Stephen R C

BACKGROUND\ud An improved understanding of childhood pneumonia aetiology is required to inform prevention and treatment strategies. Lung aspiration is the gold standard specimen for pneumonia diagnostics. We report findings from analyses of lung and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ad272d48126c5c8018334e6e49bd6a6c
https://archive.lstmed.ac.uk/15762/1/LA_manus_accepted_CID.pdf

A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to reconsider the current contraindication?

Autor: Virgilio E. Failoc-Rojas, Carlos Chaccour, Pascal Del Giudice, Jaime Piquero-Casals, Menno R. Smit, Kevin C. Kobylinski, Georgina S. Humphreys, Kasia Stepniewska, Céline Dard, Sabine Specht, Wuelton Marcelo Monteiro, Franck Boralevi, Jean T. Coulibaly, Philippe J Guerin, Antoni Soriano-Arandes, Belen Pedrique, David Wimmersberger, Lucia Romani, Marimar Sáez-De-ocariz, Kalynn Kennon, Daniel T. Engelman, Virak Khieu, Anne Faisant, Michael Marks, Marie Pierre Brenier-Pinchart, Annabel Maruani, Andrew C Steer, Podjanee Jittamala, Lorenz von Seidlein, Oliver Sokana, Eli Harriss, Nicholas J. White, Jennifer Keiser

Publikováno v: Scientia
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2021, 15 (3), pp.e0009144. ⟨10.1371/journal.pntd.0009144⟩
Jittamala, P, Monteiro, W, Smit, M R, Pedrique, B, Specht, S, Chaccour, C J, Dard, C, Del Giudice, P, Khieu, V, Maruani, A, Failoc-Rojas, V E, Saez-de-Ocariz, M, Soriano-Arandes, A, Piquero-Casals, J, Faisant, A, Brenier-Pinchart, M-P, Wimmersberger, D, Coulibaly, J T, Keiser, J, Boralevi, F, Sokana, O, Marks, M, Engelman, D, Romani, L, Steer, A C, von Seidlein, L, White, N J, Harriss, E, Stepniewska, K, Humphreys, G S, Kennon, K, Guerin, P J & Kobylinski, K C 2021, ' A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms : Is it time to reconsider the current contraindication? ', PLoS Neglected Tropical Diseases, vol. 15, no. 3, e0009144 . https://doi.org/10.1371/journal.pntd.0009144, https://doi.org/10.1371/journal.pntd.0009144
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009144 (2021)
PLoS neglected tropical diseases, 15(3):e0009144. Public Library of Science

Background Oral ivermectin is a safe broad spectrum anthelminthic used for treating several neglected tropical diseases (NTDs). Currently, ivermectin use is contraindicated in children weighing less than 15 kg, restricting access to this drug for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db236fd7638738ea115376a6eae27d14
https://hdl.handle.net/11351/6536

Malaria Chemoprevention in the Postdischarge Management of Severe Anemia

Autor: Michael Boele van Hensbroek, Nickline A Kuya, Richard Idro, Bjarne Robberstad, Eric D Onyango, Titus K Kwambai, Simon Kariuki, Meghna Desai, Victoria Watson, Kephas Otieno, Aaron M. Samuels, Duolao Wang, Feiko O. ter Kuile, Robert O. Opoka, Kamija S. Phiri, Aggrey Dhabangi, Chandy C. John

Publikováno v: New England Journal of Medicine
N Engl J Med
New England journal of medicine, 383(23), 2242-2254. Massachussetts Medical Society

BACKGROUND Children who have been hospitalized with severe anemia in areas of Africa in which malaria is endemic have a high risk of readmission and death within 6 months after discharge. No prevention strategy specifically addresses this period. MET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cc3dc6d00094906fa080cd9911c4cb
https://hdl.handle.net/11250/2758807