Zobrazeno 1 - 10
of 2 459
pro vyhledávání: '"wnt signalling"'
Autor:
Qiaohui Ying, Yujun Jiang, Changyun Sun, Yaoguang Zhang, Ruihan Gao, Hongrui Liu, Jie Guo, Minqi Li
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Diabetes, occasionally diagnosed in orthodontic patients, can impede orthodontic tooth movement (OTM) by accumulating advanced glycation end products (AGEs) in the periodontium. This accumulation impairs the osteogenic differentia
Externí odkaz:
https://doaj.org/article/4a43c5b651e04114b69626166fa81c70
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 10, Pp 01-05 (2024)
Odontogenic tumours, derived from the epithelial, ectomesenchymal, and/or mesenchymal elements of the tooth-forming apparatus, constitute a heterogeneous group of lesions that include both benign and malignant neoplasms with metastatic capabilities.
Externí odkaz:
https://doaj.org/article/119b00b3d5a746e4be46a0f1f00b10d8
Autor:
Jayanarayanan Sadanandan, Sithara Thomas, Iny Elizabeth Mathew, Zhen Huang, Spiros L Blackburn, Nitin Tandon, Hrishikesh Lokhande, Pierre D McCrea, Emery H Bresnick, Pramod K Dash, Devin W McBride, Arif Harmanci, Lalit K Ahirwar, Dania Jose, Ari C Dienel, Hussein A Zeineddine, Sungha Hong, Peeyush Kumar T
Publikováno v:
eLife, Vol 12 (2024)
The blood-brain barrier (BBB) controls the movement of molecules into and out of the central nervous system (CNS). Since a functional BBB forms by mouse embryonic day E15.5, we reasoned that gene cohorts expressed in CNS endothelial cells (EC) at E13
Externí odkaz:
https://doaj.org/article/91728f668ee24577ab941c3ffe5ed195
Autor:
Xiaomei Wang, Qiuyun Xue, Qiangjun Duan, Ziyi Sun, Yajie Wu, Shuo Yang, Pengfei Xu, Huibo Cao, Faxue Liao, Xiao Wang, Chenggui Miao
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Our previous study found that Cullin 4B (CUL4B) inhibited rheumatoid arthritis (RA) pathology through glycogen synthase kinase-3beta (GSK3β)/canonical Wnt signalling pathway. In this work, pre-experiment and bioinformatics analysis suggested that ci
Externí odkaz:
https://doaj.org/article/453ce0553a0e4b7f9db7433bc06b9f45
Publikováno v:
Bone Reports, Vol 22, Iss , Pp 101788- (2024)
Objective: To explore the effect of amyloid-β peptide (Aβ) on mandibular condyle to develop a new treatment for postmenopausal women with Temporomandibular joint osteoarthritis. Methods: A murine bone loss model was established by ovariectomy. Micr
Externí odkaz:
https://doaj.org/article/3279f129bc7043248056834355bb4e15
Publikováno v:
eLife, Vol 13 (2024)
During Caenorhabditis elegans development, multiple cells migrate long distances or extend processes to reach their final position and/or attain proper shape. The Wnt signalling pathway stands out as one of the major coordinators of cell migration or
Externí odkaz:
https://doaj.org/article/bcd5d1c3b9834f68a49c832998984e9a
Autor:
Qiuling Guo, Jingjing Chen, Qiqi Bu, Jinling Zhang, Minjie Ruan, Xiaoyu Chen, Mingming Zhao, Xiaolin Tu, Chengzhu Zhao
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101111- (2024)
Human induced pluripotent stem cell (hiPSC)-derived mesenchymal stem cells (iMSCs) are ideal candidates for the production of standardised and scalable bioengineered bone grafts. However, stable induction and osteogenic differentiation of iMSCs pose
Externí odkaz:
https://doaj.org/article/ef882ee943ac4dd29fc0512eeb56ca7a
Autor:
Kavitha Kalimuthu, Sindhu Ganapathy, Mohammad Ahmad Wadaan, Vennila Lakshmanan, Balasubramani Ravindran, Vijayalakshmi Annamalai
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 5, Pp 103181- (2024)
Background: Wnt signalling pathway, is mediated by members of T-cell factor (TCF) transcription factors family, is essential for the control of epithelial cell proliferation and death. Glucose transporter-5 (GLUT5), fructose-specific transporter, is
Externí odkaz:
https://doaj.org/article/6a1f22540ffd467c90f5c0a6e0c00f25
Drug Repurposing: Exploring Potential Anti-Cancer Strategies by Targeting Cancer Signalling Pathways
Publikováno v:
Biology, Vol 13, Iss 6, p 386 (2024)
The repurposing of previously clinically approved drugs as an alternative therapeutic approach to treating disease has gained significant attention in recent years. A multitude of studies have demonstrated various and successful therapeutic intervent
Externí odkaz:
https://doaj.org/article/ab06e3a30fa746c986e06f3af32b69b8
Autor:
Qunxia Wang, Yanzhao Liu, Jiazhen Wu, Simei Chen, Tingting Hu, Yuhan Liu, Xu Li, Xiaohang Li, Yang Wu, Jianlin Yu, Tingting Zeng, Yi Luo, Xiaoyan Hu, Li-Ming Tan
Publikováno v:
Autoimmunity, Vol 56, Iss 1 (2023)
AbstractTo detect the value of serum interleukin-17 (IL-17), tumour necrosis factor-α (TNF-α), and Dickkopf-1 (DKK-1) in rheumatoid arthritis (RA) at different disease stages. 141 RA patients were randomly obtained and diagnosed in a large tertiary
Externí odkaz:
https://doaj.org/article/c4829aebfd64492ea8b833b0183f169c