Zobrazeno 1 - 10
of 1 473
pro vyhledávání: '"whole-genome sequencing (WGS)"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Klebsiella pneumoniae is a common pathogen capable of causing a wide range of infections. Antibiotic resistance complicates treatment of these infections significantly. We are comparing resistance levels and genotypes among two collections o
Externí odkaz:
https://doaj.org/article/8d5aa19b77424351a3af088b62b52d79
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 13, Iss 1, Pp 1-12 (2024)
Abstract Background Multidrug- or rifampicin-resistant tuberculosis (TB; MDR/RR-TB) is a significant public health threat. However, the mechanisms involved in its transmission in Sichuan, China are unclear. To provide a scientific basis for MDR/RR-TB
Externí odkaz:
https://doaj.org/article/c09415a66bf84dec95af5b47aed7bfc6
Autor:
Aderonke Mary Fayanju, Bamidele Juliet Akinyele, Babayemi Olawale Oladejo, Ayodeji Charles Osunla
Publikováno v:
Bulletin of the National Research Centre, Vol 48, Iss 1, Pp 1-10 (2024)
Abstract Background This study investigated Bacillus cereus and Bacillus subtilis from food vendors in Ondo State, Nigeria. Methods A comprehensive whole-genome sequencing (WGS) analysis of Bacillus genomes, including genome assembly, plasmid predict
Externí odkaz:
https://doaj.org/article/47eca0c8d1544dc388809ad8053d3e41
Autor:
Orna Schwartz, Hanan Rohana, Maya Azrad, Anna Shor, Nir Rainy, Yasmin Maor, Lior Nesher, Orli Sagi, Avi Peretz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Biofilm formation and toxin production are some of the virulence factors of Clostridioides difficile (C. difficile), which causes hospital-acquired C. difficile infection (HA-CDI). This work investigated the prevalence and distribution of di
Externí odkaz:
https://doaj.org/article/c4d4f1546075479d819f651783e2f332
Autor:
Hsiao-Lun Wei, Ying-Shu Liao, Bo-Han Chen, Ru-Hsiou Teng, You-Wun Wang, Jui-Hsien Chang, Chien-Shun Chiou
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 38, Iss , Pp 27-34 (2024)
Objectives: Campylobacter is a significant zoonotic pathogen primarily transmitted through poultry. Our study aimed to assess antimicrobial resistance and genetic relationships among Campylobacter isolates from retail chicken meat and humans in Taiwa
Externí odkaz:
https://doaj.org/article/1ca9dc80ce2c491db7948c125d778aac
Autor:
Carole Shum, Sang Yeon Han, Bhooma Thiruvahindrapuram, Zhuozhi Wang, Jill de Rijke, Benjamin Zhang, Maria Sundberg, Cidi Chen, Elizabeth D. Buttermore, Nina Makhortova, Jennifer Howe, Mustafa Sahin, Stephen W. Scherer
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 638-647 (2024)
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas nucleases and human induced pluripotent stem cell (iPSC) technology can reveal deep insight into the genetic and molecular bases of human biology and disease. Undesired editing ou
Externí odkaz:
https://doaj.org/article/fce05ccaaede435b84e6e74474bfe7f5
Autor:
Hui Wang, Timothy S. Chang, Beth A. Dombroski, Po-Liang Cheng, Vishakha Patil, Leopoldo Valiente-Banuet, Kurt Farrell, Catriona Mclean, Laura Molina-Porcel, Alex Rajput, Peter Paul De Deyn, Nathalie Le Bastard, Marla Gearing, Laura Donker Kaat, John C. Van Swieten, Elise Dopper, Bernardino F. Ghetti, Kathy L. Newell, Claire Troakes, Justo G. de Yébenes, Alberto Rábano-Gutierrez, Tina Meller, Wolfgang H. Oertel, Gesine Respondek, Maria Stamelou, Thomas Arzberger, Sigrun Roeber, Ulrich Müller, Franziska Hopfner, Pau Pastor, Alexis Brice, Alexandra Durr, Isabelle Le Ber, Thomas G. Beach, Geidy E. Serrano, Lili-Naz Hazrati, Irene Litvan, Rosa Rademakers, Owen A. Ross, Douglas Galasko, Adam L. Boxer, Bruce L. Miller, Willian W. Seeley, Vivanna M. Van Deerlin, Edward B. Lee, Charles L. White, Huw Morris, Rohan de Silva, John F. Crary, Alison M. Goate, Jeffrey S. Friedman, Yuk Yee Leung, Giovanni Coppola, Adam C. Naj, Li-San Wang, P. S. P. genetics study group, Clifton Dalgard, Dennis W. Dickson, Günter U. Höglinger, Gerard D. Schellenberg, Daniel H. Geschwind, Wan-Ping Lee
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease characterized by the accumulation of aggregated tau proteins in astrocytes, neurons, and oligodendrocytes. Previous genome-wide association studies for PSP w
Externí odkaz:
https://doaj.org/article/855cdef1a9b046af9ac1a7a118950c99
Publikováno v:
Applied Microbiology, Vol 4, Iss 3, Pp 1142-1149 (2024)
According to a report by the World Health Organization (WHO), each year, over 550 million individuals worldwide suffer from and 230,000 die from diarrheal illnesses, which accounts for more than half of the global foodborne disease burden. Among them
Externí odkaz:
https://doaj.org/article/44b3c3001af54731a7bcc9bc07989138
Autor:
Kgaugelo Edward Lekota, Ayesha Hassim, Maphuti Betty Ledwaba, Barbara A. Glover, Edgar. H. Dekker, Louis Ockert van Schalkwyk, Jennifer Rossouw, Wolfgang Beyer, Gilles Vergnaud, Henriette van Heerden
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract The anthrax-causing bacterium Bacillus anthracis comprises the genetic clades A, B, and C. In the northernmost part (Pafuri) of Kruger National Park (KNP), South Africa, both the common A and rare B strains clades occur. The B clade strains
Externí odkaz:
https://doaj.org/article/238e8cf24b354305b4d149c909c6214c
Autor:
Yingming Zheng, Chuanping Lin, Wen-Jing Wang, Liya Wang, Yeqing Qian, Luna Mao, Baohua Li, Lijun Lou, Yuchan Mao, Na Li, Jiayong Zheng, Nan Jiang, Chaying He, Qijing Wang, Qing Zhou, Fang Chen, Fan Jin
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract The analysis of genomic variations in offspring after implantation has been infrequently studied. In this study, we aim to investigate the extent of de novo mutations in humans from developing fetus to birth. Using high-depth whole-genome se
Externí odkaz:
https://doaj.org/article/176bd970e7e9408298a768348a551c37