Zobrazeno 1 - 10
of 62
pro vyhledávání: '"whole-cell screening"'
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1415 (2023)
Biocatalytic processes are increasingly used in organic synthesis for the preparation of targeted molecules or the generation of molecular diversity. The search for the biocatalyst is often the bottleneck in the development of the process. We describ
Externí odkaz:
https://doaj.org/article/cdd390010a834db8b1a426cb05138aa0
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Efficient high-throughput drug screening assays are necessary to enable the discovery of new anti-mycobacterial drugs. The purpose of our work was to develop and validate an assay based on live-cell imaging which can monitor the g
Externí odkaz:
https://doaj.org/article/cc6617b4ccd84bd58462497f807579e7
Akademický článek
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Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Within the polymicrobial dental plaque biofilm, bacteria kill competitors by excreting mixtures of bacteriocins, resulting in improved fitness and survival. Inhibiting their bacteriocin synthesis might therefore be a useful strate
Externí odkaz:
https://doaj.org/article/6db93f4ca48e4e8ab487f44d06c99d97
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The spreading of multidrug-resistant bacteria and the lack of novel antibiotic molecules leave clinicians and veterinarians with very limited options to treat bacterial infections, especially those caused by Gram-negative pathogens. To reduce the sel
Externí odkaz:
https://doaj.org/article/d06f590808f446d191d7fa882c68331a
Akademický článek
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Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Antibiotic resistance is now a worldwide therapeutic problem. Since the beginning of anti-infectious treatment bacteria have rapidly shown an incredible ability to develop and transfer resistance mechanisms. In the last decades, the design variation
Externí odkaz:
https://doaj.org/article/0e91ee73656e4ecaad238f4f7d35e7d4
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Although efforts to identify novel therapies for the treatment of tuberculosis (TB) have led to the identification of several promising drug candidates, the identification of high-quality hits from conventional whole-cell screens remains disappointin
Externí odkaz:
https://doaj.org/article/9a7f754b9d9945d8815355abb86b0675
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Microbiology, Vol 21, Iss 1, Pp 1-14 (2021)
Background Efficient high-throughput drug screening assays are necessary to enable the discovery of new anti-mycobacterial drugs. The purpose of our work was to develop and validate an assay based on live-cell imaging which can monitor the growth of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846c8ee10ffa2166120e57153d63b3eb
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-177442
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-177442
Kniha
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