Synthesis of 6a,7b-dihydroxyvouacapan-17b-oic acid derivatives. Part IV: mannich base derivatives and its activities on the electrically stimulated Guinea-pig ileum preparation

Autor: Belinelo, Valdenir J., Reis, Genuína T., Stefani, Guglielmo M., Ferreira-Alves, Dalton L., Piló-Veloso, Dorila

Publikováno v: Journal of the Brazilian Chemical Society v.13 n.6 2002
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Vol 13, Iss 6, Pp 830-837 (2002)
Journal of the Brazilian Chemical Society, Volume: 13, Issue: 6, Pages: 830-837, Published: NOV 2002

The furanditerpene 6a,7b-dihydroxyvouacapan-17b-oic acid (ADV, 1), isolated from Pterodon polygalaeflorus Benth fruits, presents analgesic activity in current rodent experimental models. With the aim to gather data for biological studies it were obta

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