Regulator of G-protein signaling 1 critically supports CD8+ TRM cell-mediated intestinal immunity

Autor: von Werdt, Diego, Gungor, Bilgi, Barreto de Albuquerque, Juliana, Gruber, Thomas, Zysset, Daniel, Kwong Chung, Cheong K C, Corrêa-Ferreira, Antonia, Berchtold, Regina, Page, Nicolas, Schenk, Mirjam, Kehrl, John H, Merkler, Doron, Imhof, Beat A, Stein, Jens V, Abe, Jun, Turchinovich, Gleb, Finke, Daniela, Hayday, Adrian C, Corazza, Nadia, Mueller, Christoph

Publikováno v: von Werdt, Diego; Gungor, Bilgi; Barreto de Albuquerque, Juliana; Gruber, Thomas; Zysset, Daniel; Kwong Chung, Cheong K C; Corrêa-Ferreira, Antonia; Berchtold, Regina; Page, Nicolas; Schenk, Mirjam; Kehrl, John H; Merkler, Doron; Imhof, Beat A; Stein, Jens V; Abe, Jun; Turchinovich, Gleb; Finke, Daniela; Hayday, Adrian C; Corazza, Nadia and Mueller, Christoph (2023). Regulator of G-protein signaling 1 critically supports CD8+ TRM cell-mediated intestinal immunity. Frontiers in immunology, 14, p. 1085895. Frontiers Research Foundation 10.3389/fimmu.2023.1085895

Members of the Regulator of G-protein signaling (Rgs) family regulate the extent and timing of G protein signaling by increasing the GTPase activity of Gα protein subunits. The Rgs family member Rgs1 is one of the most up-regulated genes in tissue-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b00ac73376c75571c80f3fdf3b3754
https://doi.org/10.3389/fimmu.2023.1085895

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Microbial uptake in oral mucosa–draining lymph nodes leads to rapid release of cytotoxic CD8⁺ T cells lacking a gut-homing phenotype.

Autor: Barreto de Albuquerque, Juliana, Altenburger, Lukas M., Abe, Jun, von Werdt, Diego, Wissmann, Stefanie, Martínez Magdaleno, Jose, Francisco, David, van Geest, Geert, Ficht, Xenia, Iannacone, Matteo, Bruggmann, Remy, Mueller, Christoph, Stein, Jens V.

Publikováno v: Science Immunology; 2022, Vol. 7 Issue 72, p1-15, 15p

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IL-32γ potentiates tumor immunity in melanoma

Autor: Gruber, Thomas, Kremenovic, Mirela, Sadozai, Hassan, Rombini, Nives, Baeriswyl, Lukas, Maibach, Fabienne, Modlin, Robert L, Gilliet, Michel, Von Werdt, Diego, Hunger, Robert E., Jafari, S. Morteza Seyed, Parisi, Giulia, Abril-Rodriguez, Gabriel, Ribas, Antoni, Schenk, Mirjam

Myeloid cells orchestrate the antitumor immune response and influence the efficacy of immune checkpoint blockade (ICB) therapies. We and others have previously shown that IL-32 mediates DC differentiation and macrophage activation. Here, we demonstra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02294a7b032a233bf0cbf383780429f3