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Diffusion MRI indicating structural nerve recovery after microvascular decompression in trigeminal neuralgia

Autor: Dirks, F, Louçäo, R, Burg, K, von Spreckelsen, N, Hoevels, M, Lichtenstein, T, Goldbrunner, R, Hampl, JA, Weiß-Lucas, C

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV185 /20220525/

Objective: Previous studies using MRI techniques such as diffusion tensor imaging (DTI) as a diagnostic tool for trigeminal neuralgia found a significantly lower fractional anisotropy (FA) in the root-entry-zone of the affected nerve. We hypothesized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a10498801b2b32702b6140124b1a96

Novel rapid intraoperative tumour detection for resection and biopsy control by a residual convolutional neural network using stimulated raman scattering microscopy

Autor: Reinecke, D, von Spreckelsen, N, Mawrin, C, Ion-Margineanu, A, Fürtjes, G, Jünger, ST, Khalid, F, Freudiger, C, Timmer, M, Ruge, MI, Goldbrunner, R, Neuschmelting, V

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV088 /20220525/

Objective: The determination of the presence of tumor in biopsies and the decision-making during resections is often dependent on intraoperative histological tissue sample assessment. Recently, stimulated Raman scattering microscopy has been introduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2a8b5fae33635b1d3c6d17aa96119e

Mapping of genome-wide methylation pattern identifies a high-risk subgroup of intraventricular meningiomas

Autor: Ricklefs, FL, Heiland, DH, Jungwirth, G, von Spreckelsen, N, Schmidt, NO, Grauvogel, J, Masalha, W, Beck, J, Unterberg, AW, Timmer, M, Goldbrunner, R, Schüller, U, Dührsen, L, Westphal, M, Schnell, O, Herold-Mende, C, Lamszus, K

Publikováno v: 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCV214 /20210604/

Objective: Intraventricular meningiomas (IVMs) are a rare subgroup accounting for less than 5% of all intracranial meningiomas. Recent studies showed evidence that IVMs are marked by a distinct chromosomal alteration with a combined loss of chromosom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dfb6a13c0ebf386fbccb7a7c778e4e

Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican

Autor: von Spreckelsen, N, Fadzen, CM, Hartrampf, N, Ghotmi, Y, Wolfe, J, Dubey, S, Yang, BY, Kijewski, M, Wang, S, Farquhar, C, Bergmann, S, Zdioruk, M, Wasserburg, JR, Murrell, E, Bononi, FC, Luyt, LG, Di Carli, M, Lamfers, MLM, Ligon, KL, Chiocca, EA, Viapiano, MS, Pentelute, BL, Lawler, SE, Cho, CF

Publikováno v: 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP125 /20210604/

Objective: Glioblastoma (GBM) is the most common and deadliest form of brain tumor and treatment options available today have limited success. Brevican (Bcan), a central nervous system (CNS)-specific extracellular matrix protein, is upregulated in hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2420cc416b6515b077e9e74512607208