Riboflavin Supplementation Promotes Butyrate Production in the Absence of Gross Compositional Changes in the Gut Microbiota.

Autor: Liu L; Department of Medical Microbiology and Infection Prevention and University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Sadaghian Sadabad M; Department of Medical Microbiology and Infection Prevention and University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Gabarrini G; Department of Medical Microbiology and Infection Prevention and University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Lisotto P; Department of Medical Microbiology and Infection Prevention and University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., von Martels JZH; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Wardill HR; School of Biomedicine, The University of Adelaide, and Precision Medicine (Cancer), The South Australian Health and Medical Research Institute Adelaide, Adelaide, Australia.; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Steinert RE; DSM Nutritional Products AG, Kaiseraugst, Switzerland.; Department of Surgery, Division of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland., Harmsen HJM; Department of Medical Microbiology and Infection Prevention and University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Publikováno v: Antioxidants & redox signaling [Antioxid Redox Signal] 2023 Feb; Vol. 38 (4-6), pp. 282-297. Date of Electronic Publication: 2022 Oct 10.

Mucosal Eosinophil Abundance in Non-Inflamed Colonic Tissue Is Associated with Response to Vedolizumab Induction Therapy in Inflammatory Bowel Disease.

Autor: Gabriëls RY; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Bourgonje AR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., von Martels JZH; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Blokzijl T; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Galinsky K; Gastroenterology Drug Discovery Unit, Takeda Pharmaceuticals, Cambridge, MA 02139, USA., Juarez J; Gastroenterology Drug Discovery Unit, Takeda Pharmaceuticals, Cambridge, MA 02139, USA., Faber KN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Kats-Ugurlu G; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

Publikováno v: Journal of clinical medicine [J Clin Med] 2022 Jul 16; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 16.

Riboflavin Supplementation in Patients with Crohn's Disease [the RISE-UP study].

Autor: von Martels JZH; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bourgonje AR; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Klaassen MAY; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Alkhalifah HAA; Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Sadaghian Sadabad M; Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Vich Vila A; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Gacesa R; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Gabriëls RY; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Steinert RE; R&D Human Nutrition and Health, DSM Nutritional Products Ltd, Basel, Switzerland., Jansen BH; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bulthuis MLC; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Dullemen HM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., de Vos P; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Goor H; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Faber KN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Harmsen HJM; Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2020 Jun 19; Vol. 14 (5), pp. 595-607.

Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes.

Autor: Bradford ST; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia.; St Vincent's Clinical School, UNSW, Sydney, 2010, New South Wales, Australia., Nair SS; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; St Vincent's Clinical School, UNSW, Sydney, 2010, New South Wales, Australia., Statham AL; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., van Dijk SJ; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia., Peters TJ; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; St Vincent's Clinical School, UNSW, Sydney, 2010, New South Wales, Australia.; CSIRO Data61, North Ryde, 2113, New South Wales, Australia., Anwar F; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia., French HJ; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., von Martels JZH; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Sutcliffe B; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia., Maddugoda MP; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Peranec M; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Varinli H; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia.; Department of Biological Sciences, Macquarie University, North Ryde, 2019, New South Wales, Australia., Arnoldy R; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Buckley M; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; CSIRO Data61, North Ryde, 2113, New South Wales, Australia., Ross JP; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia., Zotenko E; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; St Vincent's Clinical School, UNSW, Sydney, 2010, New South Wales, Australia., Song JZ; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Stirzaker C; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; St Vincent's Clinical School, UNSW, Sydney, 2010, New South Wales, Australia., Bauer DC; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia., Qu W; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Swarbrick MM; Centre for Diabetes, Obesity and Endocrinology, The Westmead Institute, The University of Sydney, Westmead, 2145, New South Wales, Australia., Lutgers HL; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Lord RV; St. Vincent's Centre for Applied Medical Research, Sydney, 2010, New South Wales, Australia., Samaras K; Department of Endocrinology, St Vincent's Hospital, Sydney, 2010, New South Wales, Australia.; Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia., Molloy PL; CSIRO Health & Biosecurity, North Ryde, 2113, New South Wales, Australia. Peter.molloy@csiro.au., Clark SJ; Epigenetics Research Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia. s.clark@garvan.org.au.; St Vincent's Clinical School, UNSW, Sydney, 2010, New South Wales, Australia. s.clark@garvan.org.au.

Publikováno v: Scientific reports [Sci Rep] 2019 Jul 02; Vol. 9 (1), pp. 9511. Date of Electronic Publication: 2019 Jul 02.

Assessing intestinal permeability in Crohn's disease patients using orally administered 52Cr-EDTA.

Autor: von Martels JZH; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bourgonje AR; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Harmsen HJM; Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Faber KN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Publikováno v: PloS one [PLoS One] 2019 Feb 07; Vol. 14 (2), pp. e0211973. Date of Electronic Publication: 2019 Feb 07 (Print Publication: 2019).