Zobrazeno 1 - 10
of 85
pro vyhledávání: '"von Kriegsheim, Alexander"'
Autor:
Raab, Michaela, Christodoulou, Ersi, Krishnankutty, Roopesh, Gradinaru, Andreea, Walker, Alexander Daniel, Olaizola, Paula, Younger, Nicholas Thomas, Lyons, Anabel Martinez, Jarman, Edward Joseph, Gournopanos, Konstantinos, von Kriegsheim, Alexander, Waddell, Scott Hamilton, Boulter, Luke
Publikováno v:
In Journal of Hepatology July 2024 81(1):108-119
The RhoA regulators Myo9b and GEF‐H1 are targets of cyclic nucleotide‐dependent kinases in platelets
Autor:
Comer, Shane, Nagy, Zoltan, Bolado, Alfonso, von Kriegsheim, Alexander, Gambaryan, Stepan, Walter, Ulrich, Pagel, Oliver, Zahedi, René P., Jurk, Kerstin, Smolenski, Albert *
Publikováno v:
In Journal of Thrombosis and Haemostasis November 2020 18(11):3002-3012
Autor:
Schaible, Bettina, Rodriguez, Javier, Garcia, Amaya, von Kriegsheim, Alexander, McClean, Siobhán, Hickey, Caitríona, Keogh, Ciara E., Brown, Eric, Schaffer, Kirsten, Broquet, Alexis, Taylor, Cormac T.
Publikováno v:
The Journal of Infectious Diseases, 2017 May 01. 215(9), 1459-1467.
Externí odkaz:
https://www.jstor.org/stable/26364983
Autor:
Jaakkola, Panu, Mole, David R., Tian, Ya-Min, Wilson, Michael I., Gielbert, Janine, Gaskell, Simon J., von Kriegsheim, Alexander, Hebestreit, Holger F., Mukherji, Mridul, Schofield, Christopher J., Maxwell, Patrick H., Pugh, Christopher W., Ratcliffe, Peter J.
Publikováno v:
Science, 2001 Apr . 292(5516), 468-472.
Externí odkaz:
https://www.jstor.org/stable/3082778
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Li Mow Chee, Frederic, Beernaert Dominguez, Bruno, Griffith, Billie, Loftus, Alex, Kumar, Yatendra, Wills, Jimi, Lee, Martin, Valli, Jessica, Wheeler, Ann P, Armstrong, J. Douglas, Parsons, Maddy, Leigh, Irene M., Proby, Charlotte, von Kriegsheim, Alexander, Bickmore, Wendy A, Frame, Margaret C, Byron, Adam
Publikováno v:
Li Mow Chee, F, Beernaert Dominguez, B, Griffith, B, Loftus, A, Kumar, Y, Wills, J, Lee, M, Valli, J, Wheeler, A P, Armstrong, J D, Parsons, M, Leigh, I M, Proby, C, von Kriegsheim, A, Bickmore, W A, Frame, M C & Byron, A 2023, ' Mena regulates nesprin-2 to control actin– 1 nuclear lamina associations, trans-nuclear 2 membrane signalling and gene expression ', Nature Communications . https://doi.org/10.1038/s41467-023-37021-x
Interactions between cells and the extracellular matrix, mediated by integrin adhesion complexes, play key roles in fundamental cellular processes, including the sensing and transduction of mechanical cues. Here, we investigate systems-level changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::d429b09c0f7b020a1514b19eb8de7547
https://hdl.handle.net/20.500.11820/9922c453-1680-494e-a59c-20713ba22df2
https://hdl.handle.net/20.500.11820/9922c453-1680-494e-a59c-20713ba22df2
Autor:
Ryan, Eilise, Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R, Zhang, Ailiang, Howden, Andrew J M, Sanchez Garcia, Manuel Alejandro, Bewley, Martin A., Cole, Joby, McHugh, Brian, Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, von Kriegsheim, Alexander, Sanchez, Yolanda, Rumsey, William, Callahan, James F, Cooper, George, Parkinson, Nicholas, Baillie, J Kenneth, Cantrell, Doreen, McCafferty, John, Choudhury, Gourab, Singh, David, Dockrell, David H, Whyte, Moira K B, Walmsley, Sarah R
Publikováno v:
Ryan, E, Sadiku, P, Coelho, P, Watts, E R, Zhang, A, Howden, A J M, Sanchez Garcia, M A, Bewley, M A, Cole, J, McHugh, B, Vermaelen, W, Ghesquiere, B, Carmeliet, P, Rodriguez Blanco, G, von Kriegsheim, A, Sanchez, Y, Rumsey, W, Callahan, J F, Cooper, G, Parkinson, N, Baillie, J K, Cantrell, D, McCafferty, J, Choudhury, G, Singh, D, Dockrell, D H, Whyte, M K B & Walmsley, S R 2023, ' NRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD ', American Journal of Respiratory and Critical Care Medicine . https://doi.org/10.1164/rccm.202203-0482OC
Rationale: COPD (Chronic Obstructive Pulmonary Disease) is a disease characterized by persistent airway inflammation and disordered macrophage function. The extent to which alterations in macrophage bioenergetics contribute to impaired antioxidant re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::fe09787fc19ea59a2ff88a8d7a9dc9ab
https://www.pure.ed.ac.uk/ws/files/323890313/Complete_AJRCCM_MS.pdf
https://www.pure.ed.ac.uk/ws/files/323890313/Complete_AJRCCM_MS.pdf
Autor:
Vlahov, Nikola, Steenbreek, Sander, Tognoli, Maria Laura, Pankova, Daniela, Eyres, Michael, Cano-Rodriguez, David, Scrace, Simon, von Kriegsheim, Alexander, Rots, Marianne, van Rheenen, Jacco, O'Neill, Eric
Publikováno v:
Vlahov, N, Steenbreek, S, Tognoli, M L, Pankova, D, Eyres, M, Cano-Rodriguez, D, Scrace, S, von Kriegsheim, A, Rots, M, van Rheenen, J & O'Neill, E 2022, ' RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis : prev. Amoeboid cells are stem-like and induce non-cell autonomous metastasis in vivo ', EMBO Journal . https://doi.org/10.15252/embj.2021107680
Activation of the GTPase RhoA increases actinomyosin contractility and a population of highly invasive amoeboid-like cells in tumours. Here we identified that the pro-metastatic oncogene RASSF1C is an activator of RhoA/ROCK signaling and amoeboid mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::3f2773c9502572f104261d38b667a18a
https://hdl.handle.net/20.500.11820/349ea53c-7090-46b5-a6e8-139f325b25e9
https://hdl.handle.net/20.500.11820/349ea53c-7090-46b5-a6e8-139f325b25e9
Publikováno v:
Lennon, J, zur Lage, P, von Kriegsheim, A & Jarman, A 2022, ' Strongly truncated Dnaaf4 plays a conserved role in Drosophila ciliary dynein assembly as part of an R2TP-like co-chaperone complex with Dnaaf6 ', Frontiers in genetics, vol. 13, 943197 . https://doi.org/10.3389/fgene.2022.943197
Axonemal dynein motors are large multi-subunit complexes that drive ciliary movement. Cytoplasmic assembly of these motor complexes involves several co-chaperones, some of which are related to the R2TP co-chaperone complex. Mutations of these genes i
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.