Zobrazeno 1 - 10
of 1 192
pro vyhledávání: '"von Haeseler A"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Nucleotide conversion RNA sequencing techniques interrogate chemical RNA modifications in cellular transcripts, resulting in mismatch-containing reads. Biases in mapping the resulting reads to reference genomes remain poorly understood. We p
Externí odkaz:
https://doaj.org/article/82b79117ed5b4c5591dea76d334124af
We develop a Fokker-Planck theory of tissue growth with three types of cells (symmetrically dividing, asymmetrically dividing and non-dividing) as main agents to study the growth dynamics of human cerebral organoids. Fitting the theory to lineage tra
Externí odkaz:
http://arxiv.org/abs/2210.17270
Autor:
Florian G Pflug, Simon Haendeler, Christopher Esk, Dominik Lindenhofer, Jürgen A Knoblich, Arndt von Haeseler
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1012054 (2024)
Neural organoids model the development of the human brain and are an indispensable tool for studying neurodevelopment. Whole-organoid lineage tracing has revealed the number of progenies arising from each initial stem cell to be highly diverse, with
Externí odkaz:
https://doaj.org/article/875383fb62c94a9a84aa0a0fb8677bdc
Publikováno v:
BMC Bioinformatics, Vol 13, Iss 1, p 110 (2012)
Abstract Background Figures of phylogenetic trees are widely used to illustrate the result of evolutionary analyses. However, one cannot easily extract a machine-readable representation from such images. Therefore, new software emerges that helps to
Externí odkaz:
https://doaj.org/article/e7dba23532cc4733988eb655c9dcc0ee
Publikováno v:
Algorithms for Molecular Biology, Vol 5, Iss 1, p 37 (2010)
Abstract Background The availability of many gene alignments with overlapping taxon sets raises the question of which strategy is the best to infer species phylogenies from multiple gene information. Methods and programs abound that use the gene alig
Externí odkaz:
https://doaj.org/article/c2d520e9ea7c424782d89519606ea5db
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 417 (2010)
Abstract Background The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the encoded proteins undergoes a thorough experimental characterizat
Externí odkaz:
https://doaj.org/article/b757b12bd14d45ea83e6de180920c761
Publikováno v:
BMC Biology, Vol 7, Iss 1, p 68 (2009)
Abstract Background Different iron transport systems evolved in Gram-negative bacteria during evolution. Most of the transport systems depend on outer membrane localized TonB-dependent transporters (TBDTs), a periplasma-facing TonB protein and a plas
Externí odkaz:
https://doaj.org/article/c1fae28a292e4674a6f5513a0ef77ac8
Autor:
Maier Uwe G, von Haeseler Arndt, Schulerowitz Katrin, Le Sy Vinh, Tillich Michael, Schmitz-Linneweber Christian
Publikováno v:
BMC Evolutionary Biology, Vol 9, Iss 1, p 201 (2009)
Abstract Background RNA editing in chloroplasts of angiosperms proceeds by C-to-U conversions at specific sites. Nuclear-encoded factors are required for the recognition of cis-elements located immediately upstream of editing sites. The ensemble of e
Externí odkaz:
https://doaj.org/article/84563eeb797e4e55848d58ff5a25d1eb
Publikováno v:
BMC Evolutionary Biology, Vol 9, Iss 1, p 157 (2009)
Abstract Background EST sequencing is a versatile approach for rapidly gathering protein coding sequences. They provide direct access to an organism's gene repertoire bypassing the still error-prone procedure of gene prediction from genomic data. The
Externí odkaz:
https://doaj.org/article/c4a37155d62e46f489db2ca5b0e5a1b4
Autor:
Schott Matthias, Pitschke Gerald, von Haeseler Arndt, Gabbert Helmut E, Schwalen Andreas, Geddert Helene, Pardillos Guillermo G, Rosskopf Michael, Neukirchen Judith, Rohrbeck Astrid, Kronenwett Ralf, Haas Rainer, Rohr Ulrich-Peter
Publikováno v:
Journal of Translational Medicine, Vol 6, Iss 1, p 69 (2008)
Abstract Methods We examined gene expression profiles of tumor cells from 29 untreated patients with lung cancer (10 adenocarcinomas (AC), 10 squamous cell carcinomas (SCC), and 9 small cell lung cancer (SCLC)) in comparison to 5 samples of normal lu
Externí odkaz:
https://doaj.org/article/6d953c7d5eb1485a9df2686bed3fd9c4