Taking a closer look at whole organisms

Autor: Noriko Ichino, Stephen C Ekker

Publikováno v: eLife, Vol 8 (2019)

By enabling researchers to image whole zebrafish with cellular resolution, X-ray histotomography will improve our understanding of the biological differences between individuals of the same species.

Externí odkaz: https://doaj.org/article/26e4a6ec9017464684da3443f7b99281

Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography

Autor: Xianghui Xiao, Yuxin Wang, Francesco De Carlo, Darin P. Clark, Victor A. Canfield, Daniel J. Vanselow, Khai C. Ang, Keith C. Cheng, Patrick J. La Riviere, Phillip Vargas, Alex Y. Lin, Xuying Xin, Yifu Ding, Jean E. Copper, Damian B. van Rossum, Maksim A Yakovlev, Spencer R Katz

Publikováno v: eLife, Vol 8 (2019)
eLife

Organismal phenotypes frequently involve multiple organ systems. Histology is a powerful way to detect cellular and tissue phenotypes, but is largely descriptive and subjective. To determine how synchrotron-based X-ray micro-tomography (micro-CT) can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511043b4a917989f6cc6885548d0876a
https://elifesciences.org/articles/44898

Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography.

Autor: Ding Y; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States.; Medical Scientist Training Program, Penn State College of Medicine, Hershey, United States., Vanselow DJ; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Yakovlev MA; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Katz SR; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States.; Medical Scientist Training Program, Penn State College of Medicine, Hershey, United States., Lin AY; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Clark DP; Center for In Vivo Microscopy, Duke University, Durham, United States., Vargas P; Department of Radiology, The University of Chicago, Chicago, United States., Xin X; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Copper JE; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Canfield VA; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Ang KC; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., Wang Y; Imaging Group, Omnivision Technologies, Inc., Santa Clara, United States., Xiao X; National Synchrotron Light Source II, Brookhaven National Laboratory, Upton, United States., De Carlo F; Advanced Photon Source, Argonne National Laboratory, Lemont, United States., van Rossum DB; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States., La Riviere P; Department of Radiology, The University of Chicago, Chicago, United States., Cheng KC; The Jake Gittlen Laboratories for Cancer Research, Penn State College of Medicine, Hershey, United States.; Division of Experimental Pathology, Department of Pathology, Penn State College of Medicine, Hershey, United States.

Publikováno v: ELife [Elife] 2019 May 07; Vol. 8. Date of Electronic Publication: 2019 May 07.