Prospectives of developing therapeutic HPV vaccines

Autor: Natalja M. Raevskaya, T. N. Nikitina, A. S. Simbirtsev, I. L. Solovyeva, A. R. Volgin, A. S. Korovkin

Publikováno v: Инфекция и иммунитет, Vol 14, Iss 4, Pp 655-671 (2024)

Human papillomavirus (HPV) represents one of the most serious global public health problems. Malignant female and male diseases mainly result from persistent HPV infection. Cancer belongs to a high mortality rate disease. It has been established that

Externí odkaz: https://doaj.org/article/e0cb1971006f49c8af13732a2147000c

Immunogenic and Protective Features of the Recombinant Vaccinia Virus Strain Expressing Cassette of Genes of Marburg Virus Structural Proteins

Autor: A. V. Semenova, G. F. Sivolobova, A. A. Grazhdantseva, S. A. P’yankov, I. S. Shul’gina, O. S. Taranov, O. V. P’yankov, D. V. Antonets, L. I. Karpenko, E. V. Starostina, M. V. Borgoyakova, A. N. Chikaev, E. V. Gavrilova, R. A. Maksyutov, G. V. Kochneva

Publikováno v: Проблемы особо опасных инфекций, Vol 0, Iss 4, Pp 143-149 (2022)

The aim of the study was to create a highly immunogenic vaccine construct based on a recombinant variant of a replication-defective MVA strain of vaccinia virus, expressing virus-like particles that mimic natural infection with Marburg virus. Materia

Externí odkaz: https://doaj.org/article/fbb54b5d90c74b5d97a2b3af71b8c995

A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques

Autor: Ariane Volkmann, Gerrit Koopman, Petra Mooij, Ernst J. Verschoor, Babs E. Verstrepen, Willy M. J. M. Bogers, Manja Idorn, Søren R. Paludan, Søren Vang, Morten A. Nielsen, Adam F. Sander, Carolin Schmittwolf, Hubertus Hochrein, Paul Chaplin

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic. Here, we present non-human primate immunogenicity and protective efficacy data generated with the capsid virus-like particle (cVLP)-based vaccine ABNCoV2 th

Externí odkaz: https://doaj.org/article/70276a3707f448aaac6b86a678a0b8dd

Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates

Autor: Peng Xiao, Krista Dienger-Stambaugh, Xuemin Chen, Huiling Wei, Shannon Phan, Ashley C. Beavis, Karnail Singh, Nihar R. Deb Adhikary, Pooja Tiwari, Francois Villinger, Biao He, Paul Spearman

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

The search for a preventive vaccine against HIV infection remains an ongoing challenge, indicating the need for novel approaches. Parainfluenza virus 5 (PIV5) is a paramyxovirus replicating in the upper airways that is not associated with any animal

Externí odkaz: https://doaj.org/article/0812cea0affa41828faa00f55fffe1ef

A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques

Autor: Volkmann, Ariane, Koopman, Gerrit, Mooij, Petra, Verschoor, Ernst J., Verstrepen, Babs E., Bogers, Willy M.J.M., Idorn, Manja, Paludan, Søren R., Vang, Søren, Nielsen, Morten A., Sander, Adam F., Schmittwolf, Carolin, Hochrein, Hubertus, Chaplin, Paul

Publikováno v: Front. Immunol
Volkmann, A, Koopman, G, Mooij, P, Verschoor, E J, Verstrepen, B E, Bogers, W M J M, Idorn, M, Paludan, S R, Vang, S, Nielsen, M A, Sander, A F, Schmittwolf, C, Hochrein, H & Chaplin, P 2022, ' A capsid virus-like particle-based SARS-CoV-2 vaccine induces high levels of antibodies and protects Rhesus macaques ', Frontiers in Immunology, vol. 13, pp. 857440 . https://doi.org/10.3389/fimmu.2022.857440
Volkmann, A, Koopman, G, Mooij, P, Verschoor, E J, Verstrepen, B E, Bogers, W M J M, Idorn, M, Paludan, S R, Vang, S, Nielsen, M A, Sander, A F, Schmittwolf, C, Hochrein, H & Chaplin, P 2022, ' A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques ', Frontiers in Immunology, vol. 13, 857440 . https://doi.org/10.3389/fimmu.2022.857440

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic. Here, we present non-human primate immunogenicity and protective efficacy data generated with the capsid virus-like particle (cVLP)-based vaccine ABNCoV2 th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9416c490fd115b213c70e63f85aa3c9f
https://pubmed.ncbi.nlm.nih.gov/35479095