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Multispecies coinfections and presence of antibiotics shape resistance and fitness costs in a pathogenic bacterium

Autor: Ashrafi, Roghaieh, Bruneaux, Matthieu, Sundberg, Lotta‐Riina, Hoikkala, Ville, Karvonen, Anssi

Increasing antimicrobial resistance (AMR) poses a challenge for treatment of bacterial diseases. In real life, bacterial infections are typically embedded within complex multispecies communities and influenced by the environment, which can shape cost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1222::8be231dd65bf30740b85657826ff42c7
http://urn.fi/URN:NBN:fi:jyu-202306133778

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Glochidial infection by the endangered Margaritifera margaritifera (Mollusca) increased survival of salmonid host (Pisces) during experimental Flavobacterium disease outbreak

Autor: M. Motiur R. Chowdhury, Kalle Auvinen, Hanna Suonia, Jouni Taskinen, Katja Pulkkinen, Amitav Roy

Publikováno v: Parasitology Research

Co-infections are common in host-parasite interactions, but studies about their impact on the virulence of parasites/diseases are still scarce. The present study compared mortality induced by a fatal bacterial pathogen, Flavobacterium columnare betwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4988bbcf15f4650c33823ecff7ebf87
http://europepmc.org/articles/PMC8460588

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Prevalence of genetically similar Flavobacterium columnare phages across aquaculture environments reveals a strong potential for pathogen control

Autor: Runtuvuori‐Salmela, A., Kunttu, H. M. T., Laanto, E., Almeida, G. M. F., Mäkelä, K., Middelboe, M., Sundberg, L‐R.

Intensive aquaculture conditions expose fish to bacterial infections, leading to significant financial losses, extensive antibiotic use and risk of antibiotic resistance in target bacteria. Flavobacterium columnare causes columnaris disease in aquacu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1222::185fa1e319e5e2aa16af14c4691cc63b
http://urn.fi/URN:NBN:fi:jyu-202201261287

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Plasmid Viability Depends on the Ecological Setting of Hosts within a Multiplasmid Community

Autor: Given, Cindy, Penttinen, Reetta, Jalasvuori, Matti

Plasmids are extrachromosomal genetic elements, some of which disperse horizontally between different strains and species of bacteria. They are a major factor in the dissemination of virulence factors and antibiotic resistance. Understanding the ecol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1222::2fd4063194803557a4e54e8573634a14
http://urn.fi/URN:NBN:fi:jyu-202205022511

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Systematic Comparison of Epidemic and Non-Epidemic Carbapenem Resistant Klebsiella pneumoniae Strains

Autor: Koskinen, Katariina, Penttinen, Reetta, Örmälä-Odegrip, Anni-Maria, Giske, Christian G., Ketola, Tarmo, Jalasvuori, Matti

Over the past few decades, extensively drug resistant (XDR) resistant Klebsiella pneumoniae has become a notable burden to healthcare all over the world. Especially carbapenemase-producing strains are problematic due to their capability to withstand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c1cc9d681d1baca2d68484a384e7ec4
http://urn.fi/URN:NBN:fi:jyu-202103232076

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Cold water reduces the severity of parasite-inflicted damage : support for wintertime recuperation in aquatic hosts

Autor: Pekka Hyvärinen, Ines Klemme, Anssi Karvonen

The reduction in host fitness caused by parasite infections (virulence) depends on infection intensity and the degree of damage caused per parasite. Environmental conditions can shape both virulence components, but in contrast to infection intensity,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc481c46e84441ab491424f24a7edf5c
http://urn.fi/URN:NBN:fi:jyu-202110265403

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Broad thermal tolerance is negatively correlated with virulence in an opportunistic bacterial pathogen

Autor: Roghaieh Ashrafi, Lotta-Riina Sundberg, Katja Pulkkinen, Matthieu Bruneaux, Tarmo Ketola, Janne K. Valkonen

Publikováno v: Evolutionary Applications

Predicting the effects of global increase in temperatures on disease virulence is challenging, especially for environmental opportunistic bacteria, because pathogen fitness may be differentially affected by temperature within and outside host environ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce0f563eb4a4ed79a9287a2ce40998e
https://doi.org/10.1111/eva.12673

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Bacteriophage Adherence to Mucus Mediates Preventive Protection against Pathogenic Bacteria

Autor: Roghaieh Ashrafi, Lotta-Riina Sundberg, Elina Laanto, Gabriel Magno de Freitas Almeida

Publikováno v: mBio, Vol 10, Iss 6, p e01984-19 (2019)
mBio, Vol 10, Iss 6 (2019)
mBio

The mucosal surfaces of animals are habitat for microbes, including viruses. Bacteriophages—viruses that infect bacteria—were shown to be able to bind to mucus. This may result in a symbiotic relationship in which phages find bacterial hosts to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d440df726e3620be9b700c520770e39
https://doaj.org/article/78048bcdc1ec4e84a9135d6deebbfda8

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