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Analysis of Virtual Control Groups and Inter-species Concordance using Preclinical Toxicity Data

Autor: Wright, Peter

Chapter 1 (Introduction). In line with the US EPA’s “Toxicity Testing in the 21st Century: A Vision and Strategy” and the Replacement, Refinement, and Reduction (3Rs) goals for animals in toxicity testing, the current two species preclinical te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1ea83702bd3c9664405d0aa3e3fee85

Adverse muscle composition is linked to poor functional performance and metabolic comorbidities in NAFLD

Autor: Mattias Ekstedt, Jennifer Linge, Olof Dahlqvist Leinhard

Publikováno v: JHEP Reports, Vol 3, Iss 1, Pp 100197-(2021)
JHEP Reports

Background & Aims Sarcopenia and frailty are recognised as important factors in later stages of liver disease. However, their role in non-alcoholic fatty liver disease (NAFLD) is not yet fully understood. In this study we investigate the associations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64b7d5e87e73ceb0598021536bc3699
https://doi.org/10.1016/j.jhepr.2020.100197

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Adverse muscle composition is linked to poor functional performance and metabolic comorbidities in NAFLD.

Autor: Linge J; AMRA Medical AB, Linköping, Sweden.; Department of Health, Medicine and Caring Sciences, Division of Society and Health, Linköping University, Linköping, Sweden., Ekstedt M; Department of Gastroenterology and Hepatology, Linköping University, Linköping, Sweden.; Department of Health, Medicine and Caring Sciences, Division of Diagnostics and Specialist Medicine, Linköping University, Linköping, Sweden., Dahlqvist Leinhard O; AMRA Medical AB, Linköping, Sweden.; Department of Health, Medicine and Caring Sciences, Division of Diagnostics and Specialist Medicine, Linköping University, Linköping, Sweden.; Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2020 Oct 28; Vol. 3 (1), pp. 100197. Date of Electronic Publication: 2020 Oct 28 (Print Publication: 2021).