Výsledky vyhledávání - "viral tracing"

Akademický článek

An atlas of brain-bone sympathetic neural circuits in mice

Autor: Vitaly Ryu, Anisa Azatovna Gumerova, Ronit Witztum, Funda Korkmaz, Liam Cullen, Hasni Kannangara, Ofer Moldavski, Orly Barak, Daria Lizneva, Ki A Goosens, Sarah Stanley, Se-Min Kim, Tony Yuen, Mone Zaidi

Publikováno v: eLife, Vol 13 (2024)

There is clear evidence that the sympathetic nervous system (SNS) mediates bone metabolism. Histological studies show abundant SNS innervation of the periosteum and bone marrow–these nerves consist of noradrenergic fibers that immunostain for tyros

Externí odkaz: https://doaj.org/article/a8a653d789f845e8876a995a110d6788

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Akademický článek

A flowchart for adequate controls in virus-based monosynaptic tracing experiments identified Cre-independent leakage of the TVA receptor in RΦGT mice

Autor: Anna Velica, Klas Kullander

Publikováno v: BMC Neuroscience, Vol 25, Iss 1, Pp 1-9 (2024)

Abstract Background A pseudotyped modified rabies virus lacking the rabies glycoprotein (G-protein), which is crucial for transsynaptic spread, can be used for monosynaptic retrograde tracing. By coupling the pseudotyped virus with transgene expressi

Externí odkaz: https://doaj.org/article/3be0a1291616431d8760c3b576f9b7e7

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Akademický článek

Characterization of the neural circuitry of the auditory thalamic reticular nucleus and its potential role in salicylate-induced tinnitus

Autor: Qian Dai, Tong Qu, Guoming Shen, Haitao Wang

Publikováno v: Frontiers in Neuroscience, Vol 18 (2024)

IntroductionSubjective tinnitus, the perception of sound without an external acoustic source, is often subsequent to noise-induced hearing loss or ototoxic medications. The condition is believed to result from neuroplastic alterations in the auditory

Externí odkaz: https://doaj.org/article/649fe5d06ea84c68903e75919f3b0798

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Akademický článek

fMRI, LFP, and anatomical evidence for hierarchical nociceptive routing pathway between somatosensory and insular cortices

Autor: Hongyan Zhu, Yan Tao, Siqi Wang, Xutao Zhu, Kunzhang Lin, Ning Zheng, Li Min Chen, Fuqiang Xu, Ruiqi Wu

Publikováno v: NeuroImage, Vol 289, Iss , Pp 120549- (2024)

The directional organization of multiple nociceptive regions, particularly within obscure operculoinsular areas, underlying multidimensional pain processing remains elusive. This study aims to establish the fundamental organization between somatosens

Externí odkaz: https://doaj.org/article/a23a41d778e84dac9b25372787fc9359

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Akademický článek

Recombinase-independent AAV for anterograde transsynaptic tracing

Autor: Islam Faress, Valentina Khalil, Haruka Yamamoto, Szilard Sajgo, Keisuke Yonehara, Sadegh Nabavi

Publikováno v: Molecular Brain, Vol 16, Iss 1, Pp 1-4 (2023)

Abstract Viral transsynaptic labeling has become indispensable for investigating the functional connectivity of neural circuits in the mammalian brain. Adeno-associated virus serotype 1 (AAV1) allows for anterograde transneuronal labeling and manipul

Externí odkaz: https://doaj.org/article/82092d7fa8484ce4bef9c4567367ec31

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Akademický článek

hESC-derived striatal progenitors grafted into a Huntington’s disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum

Autor: Roberta Schellino, Dario Besusso, Roberta Parolisi, Gabriela B. Gómez-González, Sveva Dallere, Linda Scaramuzza, Marta Ribodino, Ilaria Campus, Paola Conforti, Malin Parmar, Marina Boido, Elena Cattaneo, Annalisa Buffo

Publikováno v: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-21 (2023)

Abstract Background Huntington’s disease (HD) is a motor and cognitive neurodegenerative disorder due to prominent loss of striatal medium spiny neurons (MSNs). Cell replacement using human embryonic stem cells (hESCs) derivatives may offer new the

Externí odkaz: https://doaj.org/article/f71569f50089476dbb34ca55c6b023b8

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Akademický článek

Use of a tissue clearing technique combined with retrograde trans-synaptic viral tracing to evaluate changes in mouse retinorecipient brain regions following optic nerve crush

Autor: Zong-Yi Zhan, Yi-Ru Huang, Lu-Wei Zhao, Ya-Dan Quan, Zi-Jing Li, Di-Fang Sun, Ya-Li Wu, Hao-Yuan Wu, Zi-Tian Liu, Kai-Li Wu, Yu-Qing Lan, Min-Bin Yu

Publikováno v: Neural Regeneration Research, Vol 18, Iss 4, Pp 913-921 (2023)

Successful establishment of reconnection between retinal ganglion cells and retinorecipient regions in the brain is critical to optic nerve regeneration. However, morphological assessments of retinorecipient regions are limited by the opacity of brai

Externí odkaz: https://doaj.org/article/927873a827d0465bb7fa872ed5dfe1b9

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Akademický článek

No evidence from complementary data sources of a direct glutamatergic projection from the mouse anterior cingulate area to the hippocampal formation

Autor: Lilya Andrianova, Steliana Yanakieva, Gabriella Margetts-Smith, Shivali Kohli, Erica S Brady, John P Aggleton, Michael T Craig

Publikováno v: eLife, Vol 12 (2023)

The connectivity and interplay between the prefrontal cortex and hippocampus underpin various key cognitive processes, with changes in these interactions being implicated in both neurodevelopmental and neurodegenerative conditions. Understanding the

Externí odkaz: https://doaj.org/article/a7bab46d08f641e3993fed3009cd125c

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Akademický článek

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