Zobrazeno 1 - 10
of 56
pro vyhledávání: '"viral rna genome"'
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1019-1044 (2022)
Similar to other RNA viruses, the emergence of Betacoronavirus relies on cross-species viral transmission, which requires careful health surveillance monitoring of protein-coding information as well as genome-wide analysis. Although the evolutionary
Externí odkaz:
https://doaj.org/article/a1c4476aa8f2427998c6b3acb70382a9
Publikováno v:
Pharmaceuticals, Vol 13, Iss 8, p 157 (2020)
The current Covid-19 pandemic has pointed out some major deficiencies of the even most advanced societies to fight against viral RNA infections. Once more, it has been demonstrated that there is a lack of efficient drugs to control RNA viruses. Aptam
Externí odkaz:
https://doaj.org/article/3882d96a9b41497b8611a59dfbe4a1ae
Akademický článek
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Publikováno v:
Pharmaceuticals, Vol 12, Iss 1, p 38 (2019)
In addition to the protein coding information, viral RNA genomes code functional information in structurally conserved units termed functional RNA domains. These RNA domains play essential roles in the viral cycle (e.g., replication and translation).
Externí odkaz:
https://doaj.org/article/d8168a55bba34c4c9763730d7437080a
Publikováno v:
Biochimie
The ongoing pandemic of COVID-19 (Coronavirus Disease-2019), a respiratory disease caused by the novel coronavirus strain, SARS-CoV-2, has affected more than 42 million people already, with more than one million deaths worldwide (as of October 25, 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b46fbebd88f14a3e1b32d079c65bd64
https://doi.org/10.1016/j.biochi.2020.10.010
https://doi.org/10.1016/j.biochi.2020.10.010
Autor:
Hwayoung Lee, Ahrim Lee, Dipesh S. Harmalkar, Kyeong Lee, Choongho Lee, Hyeseul Kang, Jieun Sung
Publikováno v:
Biomolecules & Therapeutics
Norovirus (NV) is the most common cause of viral gastroenteritis, with the potential to develop into a fatal disease in those who are immuno-compromised, and effective vaccines and treatments are still non-existent. In this study, we aimed to elucida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7453bb6661d0bf34fca9b693232971
https://pubmed.ncbi.nlm.nih.gov/34782485
https://pubmed.ncbi.nlm.nih.gov/34782485
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100357-(2021)
STAR Protocols
STAR Protocols
Summary The RNA-dependent-RNA polymerase (RdRp) from SARS-CoV-2 is an important drug target because it is responsible for viral RNA genome replication. Efficient production of recombinant RdRp is important in screening antivirals to treat COVID-19. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c71ca3d11d9bb42246c7a0bdbce57ba
http://www.sciencedirect.com/science/article/pii/S2666166721000642
http://www.sciencedirect.com/science/article/pii/S2666166721000642
Autor:
Bartlomiej P Przychodzen, Vasilios Polymeropoulos, Sandra P. Smieszek, Christos Polymeropoulos, Mihael H. Polymeropoulos
Coronaviruses remodel intracellular membranes to form specialized viral replication compartments, such as double-membrane vesicles where viral RNA genome replication takes place. Understanding the factors affecting host response is instrumental to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6da886f11117f1f376e6258d0fd0e48b
https://doi.org/10.1101/2021.01.22.21250070
https://doi.org/10.1101/2021.01.22.21250070
Akademický článek
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Autor:
Emily A. Bruce, Philip Eisenhauer, Jason Botten, Christopher M. Ziegler, Benjamin R. King, Daniel Zenklusen, Samuel Kellner
Publikováno v:
The Journal of General Virology
We report a fluorescence in situ hybridization (FISH) assay that allows the visualization of lymphocytic choriomeningitis mammarenavirus (LCMV) genomic RNAs in individual cells. We show that viral S segment genomic and antigenomic RNA, along with vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d91232ac494b1393ec0bbdbd3f6b65
https://doi.org/10.1099/jgv.0.000930
https://doi.org/10.1099/jgv.0.000930