Zobrazeno 1 - 10
of 799
pro vyhledávání: '"viral immunity"'
Autor:
Shachee Swaraj, Shashank Tripathi
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Interferons (IFNs) are multifaceted proteins that play pivotal roles in orchestrating robust antiviral immune responses and modulating the intricate landscape of host immunity. The major signaling pathway activated by IFNs is the JAK/STAT (J
Externí odkaz:
https://doaj.org/article/cb413c68edb34cd3933640e12a4caf43
Autor:
Eileen A. Moran, Karen Salas-Briceno, Wenming Zhao, Takuji Enya, Alexya N. Aguilera, Ivan Acosta, Francis Alonzo, Dara Kiani, Judith Behnsen, Catalina Alvarez, Thomas M. Keane, David J. Adams, Jingtao Lilue, Susan R. Ross
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Mammalian AIM-2-like receptor (ALR) proteins bind nucleic acids and initiate production of type I interferons or inflammasome assembly, thereby contributing to host innate immunity. In mice, the Alr locus is highly polymorphic at the sequenc
Externí odkaz:
https://doaj.org/article/dc580ccc007e4157abcf0818a77211f2
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IL-27, a member of the IL-6/IL-12 cytokine superfamily, is primarily secreted by antigen presenting cells, specifically by dendric cells, macrophages and B cells. IL-27 has antiviral activities and modulates both innate and adaptive immune responses
Externí odkaz:
https://doaj.org/article/d1d3de3d9141493fadcb5429d629ce9f
Autor:
Meng-Wei Tsai, Shing-Hwa Huang, Shyi-Jou Chen, Yu-Chieh Ling, Jing-Ya Huang, Po-Hsuan Jeng, Mei-Fei Chen, Huey-Kang Sytwu, Gu-Jiun Lin
Publikováno v:
Journal of Functional Foods, Vol 116, Iss , Pp 106212- (2024)
The first outbreak of influenza A virus (IAV), which has been circulating for many decades, has resulted in serious morbidity and mortality. The IAV epidemic has caused serious damage to human life and the economy. Following an IAV infection, lymphat
Externí odkaz:
https://doaj.org/article/cc3a9310ebc64002a235949c54834a66
Autor:
Keon-Il Im, Nayoun Kim, Junseok Lee, Ui-Hyeon Oh, Hye-Won Lee, Dong-Gun Lee, Gi-June Min, Raeseok Lee, Jinah Lee, Seungtaek Kim, Seok-Goo Cho
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10512 (2024)
Despite advances in vaccination and therapies for coronavirus disease, challenges remain due to reduced antibody longevity and the emergence of virulent variants like Omicron (BA.1) and its subvariants (BA.1.1, BA.2, BA.3, and BA.5). This study explo
Externí odkaz:
https://doaj.org/article/190d69afa7d646448ba19da57f9b9bf7
Autor:
Evan A. Elko, Heather L. Mead, Georgia A. Nelson, John A. Zaia, Jason T. Ladner, John A. Altin
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages of the Omicron variant rapidly became dominant in early 2022 and frequently cause human infections despite vaccination or prior infection with other variants. In addition t
Externí odkaz:
https://doaj.org/article/85f6027edcdb48be85135a982d242757
Autor:
Dearbhla Finnegan, Claire Connolly, Monica A. Mechoud, Jamie A. FitzGerald, Tom Beresford, Harsh Mathur, Lorraine Brennan, Paul D. Cotter, Christine E. Loscher
Publikováno v:
Foods, Vol 13, Iss 15, p 2392 (2024)
Fermented foods and ingredients, including furmenties derived from lactic acid bacteria (LAB) in dairy products, can modulate the immune system. Here, we describe the use of reconstituted skimmed milk powder to generate novel fermentates from Lactoba
Externí odkaz:
https://doaj.org/article/e1cedd4cf9f646b9a285f294a5821f0f
Autor:
Clara Di Vito, Nicolò Coianiz, Michela Calvi, Sara Terzoli, Elisa Zaghi, Simone Puccio, Alessandro Frigo, Jacopo Mariotti, Chiara De Philippis, Daniele Mannina, Barbara Sarina, Rossana Mineri, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Luca Castagna, Stefania Bramanti, Armando Santoro, Domenico Mavilio
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Haploidentical hematopoietic stem cell transplantation (h-HSCT) is a therapeutic option to cure patients affected by hematologic malignancies. The kinetics and the quality of immune-reconstitution (IR) impact the clinical outcome of h-HSCT and limit
Externí odkaz:
https://doaj.org/article/ff1e1518e9bd4fbda530dbd55204e118
Autor:
Dearbhla Finnegan, Monica A. Mechoud, Jamie A. FitzGerald, Tom Beresford, Harsh Mathur, Paul D. Cotter, Christine Loscher
Publikováno v:
Nutrients, Vol 16, Iss 8, p 1212 (2024)
Fermented foods have long been known to have immunomodulatory capabilities, and fermentates derived from the lactic acid bacteria of dairy products can modulate the immune system. We have used skimmed milk powder to generate novel fermentates using L
Externí odkaz:
https://doaj.org/article/130296968be84803b0598279b641b295
Publikováno v:
Exploration of Immunology, Vol 2, Iss 6, Pp 794-811 (2022)
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the human host can lead to various clinical manifestations, from symptomless carriers to mild to moderate to severe/critical illness. Therefore, the clinical classification
Externí odkaz:
https://doaj.org/article/0984e5ecf68d49d8bdbdaf69b522e778