Zobrazeno 1 - 10
of 78
pro vyhledávání: '"viral attenuation"'
Autor:
Miaomiao Wang, José Alejandro Bohórquez, Yoandry Hinojosa, Sara Muñoz-González, Markus Gerber, Liani Coronado, Carmen Laura Perera, Matthias Liniger, Nicolas Ruggli, Llilianne Ganges
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2037-2049 (2021)
The prevalence of low virulence classical swine fever virus (CSFV) strains makes viral eradication difficult in endemic countries. However, the determinants for natural CSFV attenuation and persistence in the field remain unidentified. The aim of the
Externí odkaz:
https://doaj.org/article/8aac59ebd64f4f68a3f91aafb6048990
Akademický článek
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Publikováno v:
Microbial Cell, Vol 7, Iss 2, Pp 32-35 (2019)
Viruses and other genetic parasites are present in virtually all forms of life. This chronic condition has led to diverse host cell adaptations such as CRISPR and RNAi, whose functions attenuate these parasites. It is hypothesized that programmed cel
Externí odkaz:
https://doaj.org/article/ba073a41f893444686d58660e45d6dfc
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Vaccination is the most effective method to date to prevent viral diseases. It intends to mimic a naturally occurring infection while avoiding the disease, exposing our bodies to viral antigens to trigger an immune response that will protect us from
Externí odkaz:
https://doaj.org/article/eafe543a960a4808b6765f4110b58474
Autor:
Jennifer K. Herrmann, Dong Eun Kim
Publikováno v:
Journal of Conservation and Museum Studies, Vol 19, Iss 1 (2021)
The COVID-19 pandemic has changed many aspects of life and how work is accomplished. Travel restrictions and health concerns have hindered courier trips, making virtual condition reports and deinstallations necessary to retrieve loans. However, trans
Externí odkaz:
https://doaj.org/article/8bedc1f7e25743cfb870cd76d0bed707
Autor:
Benjamin R. Jack, Daniel R. Boutz, Matthew L. Paff, Bartram L. Smith, James J. Bull, Claus O. Wilke
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 9, Pp 2957-2968 (2017)
A general means of viral attenuation involves the extensive recoding of synonymous codons in the viral genome. The mechanistic underpinnings of this approach remain unclear, however. Using quantitative proteomics and RNA sequencing, we explore the mo
Externí odkaz:
https://doaj.org/article/5d06a79440d84bc19a1b2c6ab1cfe2dd
Autor:
Hao-Sen Chiang, Helene Minyi Liu
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The antiviral innate immunity is the first line of host defense against virus infections. In mammalian cells, viral infections initiate the expression of interferons (IFNs) in the host that in turn activate an antiviral defense program to restrict vi
Externí odkaz:
https://doaj.org/article/5cf2150d74ef4eeea1678d03c678627e
Autor:
Sabrina Foscaldi, María Eugenia Loureiro, Claudia Sepúlveda, Carlos Palacios, María Belén Forlenza, Nora López
Publikováno v:
Pathogens, Vol 9, Iss 11, p 948 (2020)
Mammarenaviruses are enveloped and segmented negative-stranded RNA viruses that comprise several pathogenic members associated with severe human hemorrhagic fevers. Tacaribe virus (TCRV) is the prototype for the New World group of mammarenaviruses an
Externí odkaz:
https://doaj.org/article/1c1d01ad2b084e048588ec2559edb496
Publikováno v:
mSystems, Vol 3, Iss 4 (2018)
ABSTRACT Attenuated viruses have numerous applications, in particular in the context of live viral vaccines. However, purposefully designing attenuated viruses remains challenging, in particular if the attenuation is meant to be resistant to rapid ev
Externí odkaz:
https://doaj.org/article/af78da9074fa4669bf7def11a197981c
Autor:
Yoandry Hinojosa, José Alejandro Bohórquez, Miaomiao Wang, Markus Gerber, Matthias Liniger, Carmen L. Perera, Llilianne Ganges, Liani Coronado, Sara Muñoz-González, Nicolas Ruggli
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2037-2049 (2021)
Virulence
article-version (VoR) Version of Record
IRTA Pubpro. Open Digital Archive
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)
Wang, Miaomiao; Bohórquez, José Alejandro; Hinojosa, Yoandry; Muñoz-González, Sara; Gerber, Markus; Coronado, Liani; Perera, Carmen Laura; Liniger, Matthias; Ruggli, Nicolas; Ganges, Llilianne (2021). Abrogation of the RNase activity of Erns in a low virulence classical swine fever virus enhances the humoral immune response and reduces virulence, transmissibility, and persistence in pigs. Virulence, 12(1), pp. 2037-2049. Taylor & Francis 10.1080/21505594.2021.1959715
Virulence
article-version (VoR) Version of Record
IRTA Pubpro. Open Digital Archive
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)
Wang, Miaomiao; Bohórquez, José Alejandro; Hinojosa, Yoandry; Muñoz-González, Sara; Gerber, Markus; Coronado, Liani; Perera, Carmen Laura; Liniger, Matthias; Ruggli, Nicolas; Ganges, Llilianne (2021). Abrogation of the RNase activity of Erns in a low virulence classical swine fever virus enhances the humoral immune response and reduces virulence, transmissibility, and persistence in pigs. Virulence, 12(1), pp. 2037-2049. Taylor & Francis 10.1080/21505594.2021.1959715
The prevalence of low virulence classical swine fever virus (CSFV) strains makes viral eradication difficult in endemic countries. However, the determinants for natural CSFV attenuation and persistence in the field remain unidentified. The aim of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a9b21c34e84845c5345316754c7776
https://doaj.org/article/8aac59ebd64f4f68a3f91aafb6048990
https://doaj.org/article/8aac59ebd64f4f68a3f91aafb6048990