The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

Autor: Jenson Qi, Wensheng Lang, John G. Geisler, Ping Wang, Ioanna Petrounia, Selyna Mai, Charles Smith, Hossein Askari, Geoffrey T. Struble, Robyn Williams, Sanjay Bhanot, Brett P. Monia, Shariff Bayoumy, Eugene Grant, Gary W. Caldwell, Matthew J. Todd, Yin Liang, Micheal D. Gaul, Keith T. Demarest, Margery A. Connelly

Publikováno v: Journal of Lipid Research, Vol 53, Iss 6, Pp 1106-1116 (2012)

Diacylglycerol acyltransferase (DGAT) catalyzes the final step in triglyceride (TG) synthesis. There are two isoforms, DGAT1 and DGAT2, with distinct protein sequences and potentially different physiological functions. To date, the ability to determi

Externí odkaz: https://doaj.org/article/bd9cb90a4bc84a398c5c84be64b6a2a9

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency

Autor: Caroline C. van der Hoogt, Ko Willems van Dijk, Kyriakos E. Kypreos, Albert K. Groen, Nobuyo Maeda, Patrick C.N. Rensen, Gery Gerritsen, Frank G. Schaap, Louis M. Havekes, Peter J. Voshol

Publikováno v: Journal of Lipid Research, Vol 49, Iss 5, Pp 1048-1055 (2008)
Journal of lipid research, 49(5), 1048-1055. American Society for Biochemistry and Molecular Biology Inc.

Apolipoprotein E2 (apoE2)-associated hyperlipidemia is characterized by a disturbed clearance of apoE2-enriched VLDL remnants. Because excess apoE2 inhibits LPL-mediated triglyceride (TG) hydrolysis in vitro, we investigated whether direct or indirec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bcbea9645d766d25541d747346c6df

PPARα mediates the hypolipidemic action of fibrates by antagonizing FoxO1

Autor: H. Henry Dong, Jing He, Adama Kamagate, Yu Jiang, Dongming Su, Germán Perdomo, Shen Qu, Tonia Tse, Jennifer Altomonte

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

High-fructose consumption is associated with insulin resistance and diabetic dyslipidemia, but the underlying mechanism is unclear. We show in hamsters that high-fructose feeding stimulated forkhead box O1 (FoxO1) production and promoted its nuclear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6ec9c5c218e6d926d6ddbbd67fcf84
https://europepmc.org/articles/PMC2665003/

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.