Zobrazeno 1 - 10
of 1 275
pro vyhledávání: '"vascular targeting"'
Autor:
Bo He, Larissa Dymond, Kira H. Wood, Edward R. Bastow, Jiulia Satiaputra, Ji Li, Anna Johansson-Percival, Juliana Hamzah, M. Priyanthi Kumarasinghe, Mohammed Ballal, Jonathan Foo, Mikael Johansson, Hooi C. Ee, Scott W. White, Louise Winteringham, Ruth Ganss
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Gastrointestinal stromal tumors (GISTs) harbor diverse immune cell populations but so far immunotherapy in patients has been disappointing. Here, we established cord blood humanized mouse models of localized and disseminated GIST to explore the remod
Externí odkaz:
https://doaj.org/article/5f92efd8788044f3a874c385746f567f
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Primary cardiac angiosarcoma is a rare malignant soft-tissue sarcoma derived from vascular endothelial cells or lymphatic endothelial cells, with a high malignancy, poor prognosis, and a lack of effective medical therapy. This article reports on two
Externí odkaz:
https://doaj.org/article/2935b5f89d864ba18ffa506886036cef
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/21a97d5dc6f24283a4a364fd4fcbc0e3
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundImmune-checkpoint inhibitors (ICIs) represent a revolution in cancer therapy and are currently implemented as standard therapy within several cancer indications. Nevertheless, the treatment is only effective in a subset of patients, and imm
Externí odkaz:
https://doaj.org/article/136fb35175764ba49ca3ac2337f83163
Autor:
Anis Askarizadeh, Mohammad Mashreghi, Elaheh Mirhadi, Farshad Mirzavi, Vahid Heravi Shargh, Ali Badiee, Seyedeh Hoda Alavizadeh, Leila Arabi, Mahmoud Reza Jaafari
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-26 (2023)
Abstract Background Colorectal cancer is one of the prominent leading causes of fatality worldwide. Despite recent advancements within the field of cancer therapy, the cure rates and long-term survivals of patients suffering from colorectal cancer ha
Externí odkaz:
https://doaj.org/article/53af15c3c2984d28b0b3b7b4cd9f010c
Autor:
Angelo Corti, Angelina Sacchi, Anna Maria Gasparri, Matteo Monieri, Giulia Anderluzzi, Barbara Colombo, Alessandro Gori, Anna Mondino, Flavio Curnis
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature. We prepared bi- or trifun
Externí odkaz:
https://doaj.org/article/00849463fde24dd69a62718ebf14190b
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2165 (2022)
At the Nanomedicine Innovation Center (NICE) at the Erasmus MC in Rotterdam, we have approached the treatment of cancer by starting with a vision of first establishing a platform that enables us to overcome the low levels of drugs delivered to tumors
Externí odkaz:
https://doaj.org/article/a6c82d5b87c14d84b2895aa26a97f8ab
Autor:
Angelina Sacchi, Anna Maria Gasparri, Matteo Monieri, Giulia Anderluzzi, Barbara Colombo, Alessandro Gori, Angelo Corti, Flavio Curnis
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Gold nanoparticles functionalized with isoDGR, a tripeptide motif that recognizes αvβ3 integrin overexpressed in tumor vessels, have been used as nano-vectors for the delivery of cytokines to tumors. Functionalization of nanogold with this peptide
Externí odkaz:
https://doaj.org/article/c3578803b4ae4af89e08050241de262f
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