Long-term clinical and radiological effectiveness and safety of ultralow doses of rituximab in rheumatoid arthritis: observational extension of the REDO trial

Autor: Nathan den Broeder, Aatke van der Maas, Alfons A den Broeder, Bart JF van den Bemt, Frank HJ van den Hoogen, Yael A de Man, Marc R Kok, Lise Verhoef, Rogier Thurlings, Wilfred van der Weele

Publikováno v: RMD Open, Vol 10, Iss 2 (2024)

Background The REDO trial (REtreatment with Rituximab in RhEmatoid arthritis: Disease Outcome after Dose Optimisation) showed similar disease activity for retreatment with ultralow doses (200 mg and 500 mg per 6 months) compared with standard low-dos

Externí odkaz: https://doaj.org/article/12646c2bca3040469a48a59a6f5fa167

TCRβ clones in muscle tissue share structural features in patients with idiopathic inflammatory myopathy and are associated with disease activity

Autor: Dornatien C. Anang, Hannah A. W. Walter, Johan Lim, Ilse T. G. Niewold, Linda van der Weele, Eleonora Aronica, Filip Eftimov, Joost Raaphorst, Barbera D. C. van Schaik, Antoine H. C. van Kampen, Anneke J. van der Kooi, Niek de Vries

Publikováno v: Frontiers in Immunology, Vol 14 (2024)

ObjectivesTo characterize the T cell receptor (TCRβ) repertoire in peripheral blood and muscle tissues of treatment naïve patients with newly diagnosed idiopathic inflammatory myopathies (IIMs).MethodsHigh throughput RNA sequencing of the TCRβ cha

Externí odkaz: https://doaj.org/article/b2ad55ba571d4957af3d083ad5bd7cc6

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Technical Design Report for the PANDA Endcap Disc DIRC

Autor: Panda Collaboration, Davi, F., Erni, W., Krusche, B., Steinacher, M., Walford, N., Liu, H., Liu, Z., Liu, B., Shen, X., Wang, C., Zhao, J., Albrecht, M., Erlen, T., Feldbauer, F., Fink, M., Freudenreich, V., Fritsch, M., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kuhlmann, M., Kümmel, M., Leiber, S., Musiol, P., Mustafa, A., Pelizäus, M., Pitka, A., Reicherz, G., Richter, M., Schnier, C., Schröder, T., Sersin, S., Sohl, L., Sowa, C., Steinke, M., Triffterer, T., Wiedner, U., Beck, R., Hammann, C., Hartmann, J., Ketzer, B., Kube, M., Rossbach, M., Schmidt, C., Schmitz, R., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Czyzycki, W., Domagala, M., Filo, G., Jaworowski, J., Krawczyk, M., Lisowski, E., Lisowski, F., Michalek, M., Plazek, J., Korcyl, K., Kozela, A., Kulessa, P., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Fiutowski, T., Idzik, M., Mindur, B., Swientek, K., Biernat, J., Kamys, B., Kistryn, S., Korcyl, G., Krzemien, W., Magiera, A., Moskal, P., Przygoda, W., Rudy, Z., Salabura, P., Smyrski, J., Strzempek, P., Wronska, A., Augustin, I., Böhm, R., Lehmann, I., Marinescu, D. Nicmorus, Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Veis, N. Divani, Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Karabowicz, R., Kurilla, U., Lehmann, D., Löchner, S., Lühning, J., Lynen, U., Nakhoul, S., Orth, H., Peters, K., Saito, T., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Wilms, A., Abazov, V., Alexeev, G., Arefiev, V. A., Astakhov, V., Barabanov, M. Yu., Batyunya, B. V., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Lobanov, V. I., Malyshev, V., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Sapozhnikov, M. G., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Zinchenko, A., Branford, D., Glazier, D., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Stelter, S., Uhlig, F., Dobbs, S., Seth, K., Tomaradze, A., Xiao, T., Bettoni, D., Ali, A., Hamdi, A., Krebs, M., Nerling, F., Akishina, V., Gorbunov, S., Kisel, I., Kozlov, G., Pugach, M., Zyzak, M., Bianchi, N., Gianotti, P., Guaraldo, C., Lucherini, V., Bracco, G., Bodenschatz, S., Brinkmann, K. T., Di Pietro, V., Diehl, S., Dormenev, V., Düren, M., Etzelmüller, E., Föhl, K., Galuska, M., Geßler, T., Gutz, E., Hahn, C., Hayrapetyan, A., Kesselkaul, M., Kühn, W., Kuske, T., Lange, J. S., Liang, Y., Metag, V., Moritz, M., Nanova, M., Novotny, R., Quagli, T., Riccardi, A., Rieke, J., Schmidt, M., Schnell, R., Stenzel, H., Strickert, M., Thöring, U., Wasem, T., Wohlfahrt, B., Zaunick, H. G., Tomasi-Gustafsson, E., Ireland, D., Rosner, G., Seitz, B., Deepak, P. N., Kulkarni, A., Apostolou, A., Babai, M., Kavatsyuk, M., Loehner, H., Messchendorp, J., Schakel, P., Tiemens, M., van der Weele, J. C., Vejdani, S., Dutta, K., Kalita, K., Sohlbach, H., Bai, M., Bianchi, L., Büscher, M., Derichs, A., Dosdall, R., Erven, A., Fracassi, V., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kemmerling, G., Kleines, H., Lai, A., Lehrach, A., Mikirtychyants, M., Orfanitski, S., Prasuhn, D., Prencipe, E., Pütz, J., Ritman, J., Rosenthal, E., Schadmand, S., Sefzick, T., Serdyuk, V., Sterzenbach, G., Stockmanns, T., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Li, Z., Ma, X., Rigato, V., Isaksson, L., Achenbach, P., Aycock, A., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Merkel, H., Müller, U., Pochodzalla, J., Sanchez, S., Schlimme, S., Sfienti, C., Thiel, M., Zambrana, M., Ahmadi, H., Ahmed, S., Bleser, S., Capozza, L., Cardinali, M., Dbeyssi, A., Ehret, A., Fröhlich, B., Grasemann, P., Haasler, S., Izard, D., Jorge, J., Khaneft, D., Klasen, R., Kliemt, R., Köhler, J., Leithoff, H. H., Lin, D., Maas, F., Maldaner, S., Michel, M., Espi, M. C. Mora, Morales, C. Morales, Motzko, C., Noll, O., Pflüger, S., Pineiro, D. Rodriguez, Steinen, M., Walaa, E., Wolff, S., Zimmermann, I., Fedorov, A., Korzhik, M., Missevitch, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Goryachev, V., Kirin, D. Y., Matveev, V. A., Stavinskiy, A. V., Balashoff, A., Boukharov, A., Malyshev, O., Marishev, I., Chandratre, V., Datar, V., Jha, V., Kumawat, H., Mohanty, A. K., Parmar, A., Rai, A. K., Roy, B., Sonika, G., Fritzsch, C., Grieser, S., Hergemöller, A. K., Hetz, B., Hüsken, N., Khoukaz, A., Wessels, J. P., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Srisawad, P., Yan, Y., Blinov, A. E., Kononov, S., Kravchenko, E. A., Antokhin, E., Barnyakov, M., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Bobrovnikov, V. S., Kuyanov, I. A., Onuchin, A. P., Pivovarov, S., Pyata, E., Serednyakov, S., Tikhonov, Y., Kunne, R., Marchand, D., Ramstein, B., van de Wiele, J., Wang, Y., Boca, G., Burian, V., Finger, M., Nikolovova, A., Pesek, M., Peskova, M., Pfeffer, M., Prochazka, I., Slunecka, M., Gallus, P., Jary, V., Novy, J., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Belikov, N., Bukreeva, S., Davidenko, A., Derevschikov, A., Goncharenko, Y., Grishin, V., Kachanov, V., Kormilitsin, V., Levin, A., Melnik, Y., Minaev, N., Mochalov, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Roy, U., Yabsley, B., Belostotski, S., Gavrilov, G., Izotov, A., Manaenkov, S., Miklukho, O., Veretennikov, D., Zhdanov, A., Bäck, T., Cederwall, B., Makonyi, K., Preston, M., Tegner, P. E., Wölbing, D., Godre, S., Bussa, M. P., Marcello, S., Spataro, S., Iazzi, F., Introzzi, R., Lavagno, A., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Rivetti, A., Wheadon, R., Martin, A., Calen, H., Andersson, W. Ikegami, Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Pettersson, J., Regina, J., Schönning, K., Wolke, M., Diaz, J., Chackara, V. Pothodi, Chlopik, A., Kesik, G., Melnychuk, D., Slowinski, B., Trzcinski, A., Wojciechowski, M., Wronka, S., Zwieglinski, B., Bühler, P., Marton, J., Steinschaden, D., Suzuki, K., Widmann, E., Zimmermann, S., Zmeskal, J.

PANDA (anti-Proton ANnihiliation at DArmstadt) is planned to be one of the four main experiments at the future international accelerator complex FAIR (Facility for Antiproton and Ion Research) in Darmstadt, Germany. It is going to address fundamental

Externí odkaz: http://arxiv.org/abs/1912.12638

Adverse health effects after breast cancer up to 14 years after diagnosis

Autor: Marianne J. Heins, Kelly M. de Ligt, Janneke Verloop, Sabine Siesling, Joke C. Korevaar, Annette Berendsen, PhD, Daan Brandenbarg, PhD, Anneriet Dassen, MD PhD, Agnes Jager, MD PhD, Jacqueline Hugtenburg, PhD, Gerda van der Weele, PhD

Publikováno v: Breast, Vol 61, Iss , Pp 22-28 (2022)

Background: The number of breast cancer survivors increases, but information about long-term adverse health effects in breast cancer survivors is sparse. We aimed to get an overview of the health effects for which survivors visit their general practi

Externí odkaz: https://doaj.org/article/723bb6c16208429898c553131ddf66ee