Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

Autor: Jordi Berenguer, Tonny Lagerweij, Xi Wen Zhao, Sophie Dusoswa, Petra van der Stoop, Bart Westerman, Mark C. de Gooijer, Marloes Zoetemelk, Anoek Zomer, Matheus H. W. Crommentuijn, Laurine E. Wedekind, Àlan López-López, Alberta Giovanazzi, Marina Bruch-Oms, Ida H. van der Meulen-Muileman, Rogier M. Reijmers, Toin H. van Kuppevelt, Juan-Jesús García-Vallejo, Yvette van Kooyk, Bakhos A. Tannous, Pieter Wesseling, Danijela Koppers-Lalic, W. Peter Vandertop, David P. Noske, Victor W. van Beusechem, Jacco van Rheenen, D. Michiel Pegtel, Olaf van Tellingen, Thomas Wurdinger

Publikováno v: Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)

Cancer cells release extracellular vesicles (EVs) that contain functional biomolecules such as RNA and proteins. EVs are transferred to recipient cancer cells and can promote tumour progression and therapy resistance. Through RNAi screening, we ident

Externí odkaz: https://doaj.org/article/0383b1c10fde4f49b4ec2946fa595f3c

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Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells.

Autor: Petra van der Stoop, Erwin A Boutsma, Danielle Hulsman, Sonja Noback, Mike Heimerikx, Ron M Kerkhoven, J Willem Voncken, Lodewyk F A Wessels, Maarten van Lohuizen

Publikováno v: PLoS ONE, Vol 3, Iss 5, p e2235 (2008)

Polycomb repressive complex 1 (PRC1) core member Ring1b/Rnf2, with ubiquitin E3 ligase activity towards histone H2A at lysine 119, is essential for early embryogenesis. To obtain more insight into the role of Ring1b in early development, we studied i

Externí odkaz: https://doaj.org/article/72cd3015ec06429d8a7c567a79714969

Absence of T(H)2 cytokine messenger RNA expression in CD30-negative primary cutaneous large T-cell lymphomas

Autor: Vermeer, M H, Tensen, C P, van der Stoop, P M, van Oostveen, H W, Lund, Marianne, Scheper, R J, Willemze, R

Publikováno v: Vermeer, M H, Tensen, C P, van der Stoop, P M, van Oostveen, H W, Lund, M, Scheper, R J & Willemze, R 2001, ' Absence of T(H)2 cytokine messenger RNA expression in CD30-negative primary cutaneous large T-cell lymphomas ', Archives of Dermatology, vol. 137, no. 7, pp. 901-5 .

Previous studies demonstrating that the neoplastic cells in Sézary syndrome and tumor stage mycosis fungoides express interleukin 4 (IL-4), IL-5, and IL-10 have resulted in the concept that cutaneous T-cell lymphomas are derived from CD4(+) T cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::7febd6a1abb4bed65e340549552ebf31
https://pure.au.dk/portal/da/publications/absence-of-th2-cytokine-messenger-rna-expression-in-cd30negative-primary-cutaneous-large-tcell-lymphomas(167f65bc-cbf6-469f-a945-82f038562418).html

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