Zobrazeno 1 - 10
of 1 543
pro vyhledávání: '"van der Spek, P."'
Autor:
Claudi Bockting, Guy Bosmans, Nele Bergers, Luana Gavan, Mickaël Hiligsmann, Derek de Beurs, Geert Molenberghs, Ben Wijnen, Joran Lokkerbol, Nadia van der Spek
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Young adult suicidality is worldwide a prevalent mental health problem and the number one cause of death, with devastating consequences for individuals and their families, and substantial economic costs. However, psychological and
Externí odkaz:
https://doaj.org/article/638e8f10686e48fb91655120934236d1
Autor:
Daniël P.C. van der Spek, Caroline D. van der Marel, Cecile C. de Vos, Frank J.P.M. Huygen, Maaike Dirckx
Publikováno v:
Case Reports in Women's Health, Vol 44, Iss , Pp e00652- (2024)
Neurostimulation, for example dorsal root ganglion stimulation (DRGS), is increasingly used for managing chronic pain, including among women of reproductive age. We present the case of a 33-year-old patient with complex regional pain syndrome (CRPS)
Externí odkaz:
https://doaj.org/article/49870e8c8fb34a7ea3af2b01ae9092bd
Autor:
Lorraine Soares De Oliveira, Joseph E. Kaserman, Anne H. Van Der Spek, Nora J. Lee, Hendrik J. Undeutsch, Rhiannon B. Werder, Andrew A. Wilson, Anthony N. Hollenberg
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102057- (2024)
Objective: Thyroid hormone (TH) action is mediated by thyroid hormone receptor (THR) isoforms. While THRβ1 is likely the main isoform expressed in liver, its role in human hepatocytes is not fully understood. Methods: To elucidate the role of THRβ1
Externí odkaz:
https://doaj.org/article/f7b75a417d61423ebf131321c17d4271
Autor:
Lotte T. W. Vissers, Monique M. van Ostaijen-ten Dam, Janine E. Melsen, Yanna M. van der Spek, Koen P. Kemna, Arjan C. Lankester, Mirjam van der Burg, Alexander B. Mohseny
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPediatric patients with unexplained bone marrow failure (BMF) are often categorized as aplastic anemia (AA). Based on the accepted hypothesis of an auto-immune mechanism underlying AA, immune suppressive therapy (IST) might be effective.
Externí odkaz:
https://doaj.org/article/de9be97ece80469b94e05e49065f4ca4
Autor:
L. Van der Spek, B. G. J. S. Sonneveld
Publikováno v:
Journal of Health, Population and Nutrition, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Timor-Leste’s food insecurity, propelled by political conflicts, a fragile economy and biophysical limitations that characterize mountainous Small Island Developing States (SIDS), is expressed in a high incidence (50%) of stunte
Externí odkaz:
https://doaj.org/article/5cc8be629ec04434885c484f78294a1f
Fast estimation of Kendall's Tau and conditional Kendall's Tau matrices under structural assumptions
Kendall's tau and conditional Kendall's tau matrices are multivariate (conditional) dependence measures between the components of a random vector. For large dimensions, available estimators are computationally expensive and can be improved by averagi
Externí odkaz:
http://arxiv.org/abs/2204.03285
Bioinformatic meta-analysis reveals novel differentially expressed genes and pathways in sarcoidosis
Autor:
Rogier T. A. van Wijck, Hari S. Sharma, Sigrid M. A. Swagemakers, Willem A. Dik, Hanna IJspeert, Virgil A. S. H. Dalm, Paul L. A. van Daele, P. Martin van Hagen, Peter J. van der Spek
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionSarcoidosis is a multi-system inflammatory disease of unknown origin with heterogeneous clinical manifestations varying from a single organ non-caseating granuloma site to chronic systemic inflammation and fibrosis. Gene expression studie
Externí odkaz:
https://doaj.org/article/f8a6d8e6b3d74c478ef8b365b23c0637
Autor:
Mario F. Gely, Adrián Sanz Mora, Shun Yanai, Rik van der Spek, Daniel Bothner, Gary A. Steele
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Abstract Nonlinear damping, the change in damping rate with the amplitude of oscillations plays an important role in many electrical, mechanical and even biological oscillators. In novel technologies such as carbon nanotubes, graphene membranes or su
Externí odkaz:
https://doaj.org/article/45a3fe996d3c4c158f690496a0732232
Autor:
Gely, Mario F., Mora, Adrián Sanz, Yanai, Shun, van der Spek, Rik, Bothner, Daniel, Steele, Gary A.
Nonlinear damping, a force of friction that depends on the amplitude of motion, plays an important role in many electrical, mechanical and even biological oscillators. In novel technologies such as carbon nanotubes, graphene membranes or superconduct
Externí odkaz:
http://arxiv.org/abs/2104.06464
Autor:
Eelke M. Bos, Elena Binda, Iris S.C. Verploegh, Eva Wembacher, Daphna Hoefnagel, Rutger K. Balvers, Anne L. Korporaal, Andrea Conidi, Esther A. H. Warnert, Nadia Trivieri, Alberto Visioli, Paola Zaccarini, Laura Caiola, Rogier van Wijck, Peter van der Spek, Danny Huylebroeck, Sieger Leenstra, Martine L.M. Lamfers, Zvi Ram, Manfred Westphal, David Noske, Federico Legnani, Francesco DiMeco, Angelo Luigi Vescovi, Clemens M.F. Dirven
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone Morphogenetic Protein 4 (hrBMP4) – an inhibitory regulator of cancer stem cells (CSCs) – in
Externí odkaz:
https://doaj.org/article/b6e88963f885415e8d912afbaecd0fc3