Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease

Autor: Awoniyi, DO, Teuchert, A, Sutherland, JS, Mayanja-Kizza, H, Howe, R, Mihret, A, Loxton, AG, Sheehama, J, Kassa, D, Crampin, AC, Dockrell, HM, Kidd, M, Rosenkrands, I, Geluk, A, Ottenhoff, TH, Corstjens, PL, Chegou, NN, Walzl, G, AE-TBC Consortium, COLLABORATORS, Kriel, M, van der Spuy, G, Stanley, K, Malherbe, S, Mcanda, S, Kriel, B, Phalane, KG, Essone, P, Owolabi, O, Sillah, A, Mendy, J, Gindeh, A, Donkor, S, Togun, T, Ota, M, Simukonda, F, Amberbir, A, Chilongo, F, Houben, R, Gebrezgeabher, A, Mesfin, G, Belay, Y, Gebremichael, G, Alemayehu, Y, van der Vyver, M, Amutenya, FN, Nelongo, JN, Monye, L, Sheehama, JA, Iipinge, S, Namuganga, AR, Muzanye, G, Nsereko, M, Peters, P, Bekele, Y, Tessema, B, Yamuah, L, Franken, K, Tjon Kon Fat, EM, de Dood, CJ, van der Ploeg-van Schip, JJ, Aagaard, C, Kaufmann, SH, Esterhuyse, MM, Cliff, JM

We investigated the accuracy of host markers detected in Mtb antigen-stimulated whole blood culture supernatant in the diagnosis of TB. : Prospectively, blood from 322 individuals with presumed TB disease from six African sites was stimulated with fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::995f50199fe9304958c83397c73b9576

Whole blood RNA signatures in leprosy patients identify reversal reactions before clinical onset: a prospective, multicenter study.

Autor: Tió-Coma M; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., van Hooij A; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Bobosha K; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., van der Ploeg-van Schip JJ; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Banu S; International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh., Khadge S; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal., Thapa P; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal., Kunwar CB; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal., Goulart IM; National Reference Center for Sanitary Dermatology and Leprosy, Faculty of Medicine, Federal University of Uberlandia, Minas Gerais, Brazil., Bekele Y; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Hagge DA; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal., Moraes MO; Leprosy Laboratory, Oswaldo Cruz Institute - FIOCRUZ, Rio de Janeiro, Brazil., Teles RMB; Division of Dermatology, Department of Medicine, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California (UCLA), Los Angeles, CA, USA., Pinheiro RO; Leprosy Laboratory, Oswaldo Cruz Institute - FIOCRUZ, Rio de Janeiro, Brazil., van Zwet EW; Dept. Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands., Goeman JJ; Dept. Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands., Aseffa A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Haks MC; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Ottenhoff THM; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Modlin RL; Division of Dermatology, Department of Medicine, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California (UCLA), Los Angeles, CA, USA.; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California (UCLA), Los Angeles, CA, USA., Geluk A; Dept. of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands. a.geluk@lumc.nl.

Publikováno v: Scientific reports [Sci Rep] 2019 Nov 29; Vol. 9 (1), pp. 17931. Date of Electronic Publication: 2019 Nov 29.

Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal.

Autor: Khadge S; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal. saraswotikhadge@gmail.com., Banu S; International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh. sbanu@icddrb.org., Bobosha K; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. kbobosha@gmail.com.; Armauer Hansen Research Institute, Addis Ababa, Ethiopia. kbobosha@gmail.com., van der Ploeg-van Schip JJ; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. jjvanschip@hotmail.com., Goulart IM; National Reference Center for Sanitary Dermatology and Leprosy, Faculty of Medicine, Federal University of Uberlandia, Minas Gerais, Brazil. isagoulart@centershop.com.br., Thapa P; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal. pratibhathapakunwar@gmail.com., Kunwar CB; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal. kunwarcb@yahoo.co.uk., van Meijgaarden KE; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. K.E.van_Meijgaarden@lumc.nl., van den Eeden SJ; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. S.J.F.van_den_Eeden@lumc.nl., Wilson L; International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh. G.L.Wilson@lumc.nl., Kabir S; International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh. senjuti.kabir@icddrb.org., Dey H; International Center for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh. hymonti7@gmail.com., Goulart LR; National Reference Center for Sanitary Dermatology and Leprosy, Faculty of Medicine, Federal University of Uberlandia, Minas Gerais, Brazil. goulartlr@gmail.com., Lobato J; National Reference Center for Sanitary Dermatology and Leprosy, Faculty of Medicine, Federal University of Uberlandia, Minas Gerais, Brazil. janaina01@yahoo.com., Carvalho W; National Reference Center for Sanitary Dermatology and Leprosy, Faculty of Medicine, Federal University of Uberlandia, Minas Gerais, Brazil. washingtonjcarvalho@yahoo.com.br., Bekele Y; Armauer Hansen Research Institute, Addis Ababa, Ethiopia. yoni4m@gmail.com., Franken KL; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. C.L.M.C.Franken@lumc.nl., Aseffa A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia. aseffaa@gmail.com., Spencer JS; Dept. of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, USA. John.Spencer@colostate.edu., Oskam L; National Reference Center for Sanitary Dermatology and Leprosy, Faculty of Medicine, Federal University of Uberlandia, Minas Gerais, Brazil. l.oskam@kit.nl., Otttenhoff TH; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. t.h.m.ottenhoff@lumc.nl., Hagge DA; Mycobacterial Research Laboratories, Anandaban Hospital, Kathmandu, Nepal. deannahagge@gmail.com., Geluk A; Dept. of Infectious Diseases, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands. ageluk@lumc.nl.

Publikováno v: BMC infectious diseases [BMC Infect Dis] 2015 Oct 28; Vol. 15, pp. 477. Date of Electronic Publication: 2015 Oct 28.

Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae.

Autor: Bobosha K; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Tjon Kon Fat EM; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands., van den Eeden SJ; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Bekele Y; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., van der Ploeg-van Schip JJ; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., de Dood CJ; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands., Dijkman K; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Franken KL; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Wilson L; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Aseffa A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Spencer JS; Department of Microbiology, Immunology & Pathology, Colorado State University, Fort Collins, Colorado, United States of America., Ottenhoff TH; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Corstjens PL; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands., Geluk A; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2014 May 08; Vol. 8 (5), pp. e2845. Date of Electronic Publication: 2014 May 08 (Print Publication: 2014).

Longitudinal immune responses and gene expression profiles in type 1 leprosy reactions.

Autor: Geluk A; Department of Infectious Diseases, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands, ageluk@lumc.nl., van Meijgaarden KE, Wilson L, Bobosha K, van der Ploeg-van Schip JJ, van den Eeden SJ, Quinten E, Dijkman K, Franken KL, Haisma EM, Haks MC, van Hees CL, Ottenhoff TH

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2014 Feb; Vol. 34 (2), pp. 245-55. Date of Electronic Publication: 2013 Dec 27.