Stereoselective synthesis of functionalized bicyclic scaffolds by passerini 3-center-2-component reactions of cyclic ketoacids

Autor: Cioc, Razvan C., Estevez, Veronica, van der Niet, Daan J., Vande Velde, Christophe M. L., Turrini, Nikolaus G., Hall, Melanie, Faber, Kurt, Ruijter, Eelco, Orru, Romano V. A.

Publikováno v: European journal of organic chemistry
Cioc, R C, Estevez, V, van der Niet, D J, Vande Velde, C M L, Turrini, N G, Hall, M, Faber, K, Ruijter, E & Orru, R V A 2017, ' Stereoselective Synthesis of Functionalized Bicyclic Scaffolds by Passerini 3-Center-2-Component Reactions of Cyclic Ketoacids ', European Journal of Organic Chemistry, vol. 2017, no. 9, pp. 1262-1271 . https://doi.org/10.1002/ejoc.201601432
European Journal of Organic Chemistry, 2017(9), 1262-1271. Wiley-VCH Verlag

We report the use of bifunctional starting materials (ketoacids) in a diastereoselective Passerini three-center-two-component reaction. Study of the reaction scope revealed the required structural features for stereoselectivity in the isocyanide addi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ec3dc33152b5f5325989f0c4e4bd3081
https://hdl.handle.net/10067/1425210151162165141

Biocatalytic access to nonracemic γ-oxo esters via stereoselective reduction using ene-reductases.

Autor: Turrini, Nikolaus G., Cioc, Răzvan C., van der Niet, Daan J. H., Ruijter, Eelco, Orru, Romano V. A., Hall, Mélanie, Faber, Kurt

Publikováno v: Green Chemistry; 1/21/2017, Vol. 19 Issue 2, p511-518, 8p