Retinoid metabolism and all-trans retinoic acid-induced growth inhibition in head and neck squamous cell carcinoma cell lines.

Autor: Braakhuis, BJM, Klaassen, I, van der Leede, BM, Cloos, J, Brakenhoff, RH, Copper, MP, Teerlink, T, Hendriks, HFJ, van der Saag, PT, Snow, GB, Braakhuis, B J, van der Leede, B M, Brakenhoff, R H, Copper, M P, Hendriks, H F, van der Saag, P T, Snow, G B

Publikováno v: British Journal of Cancer; Jul1997, Vol. 76 Issue 2, p189-197, 9p

Revisiting the bacterial mutagenicity assays: Report by a workgroup of the International Workshops on Genotoxicity Testing (IWGT).

Autor: Schoeny R; Rita Schoeny, LLC, Washington, DC 20002, United States. Electronic address: ritas50@verizon.net., Cross KP; Leadscope, Inc., 1393 Dublin Road, Columbus, OH 43215, United States., DeMarini DM; U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, United States., Elespuru R; U.S. Food and Drug Administration, Center for Devices and Radiological Health, Silver Spring, MD 20993, United States., Hakura A; Tsukuba Drug Safety, Eisai Co., Ltd., Tsukuba, Ibaraki, 300-2635, Japan., Levy DD; U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD 20740 United States., Williams RV; Lhasa Limited, 2 Canal Wharf, Leeds, LS11 5PS, United Kingdom., Zeiger E; Errol Zeiger Consulting, 800 Indian Springs Road, Chapel Hill, NC 27514, United States., Escobar PA; Merck & Co., West Point, PA 19486, United States., Howe JR; GSK R&D, Hertfordshire, United Kingdom., Kato M; CMIC Pharma Science Co., Ltd., Hokuto, Yamanashi, Japan., Lott J; Boehringer Ingelheim Pharma GmbH & Co., KG, Birkendorfer Strasse 65, 88397 Biberach an der Riss, Germany., Moore MM; Ramboll US Corporation Little Rock, AR 72223, United States., Simon S; Merck KGaA, Frankfurter Straβe 250, Darmstadt, 64293, Germany., Stankowski LF Jr; Charles River Laboratories - Skokie, LLC, 8025 Lamon Ave., Skokie, IL 60077, United States., Sugiyama KI; Division of Genetics and Mutagenesis, National Institute of Health Sciences, Kawasaki, Kanagawa, 210-9501, Japan., van der Leede BM; Non-Clinical Safety Janssen R&D, a Division of Janssen Pharmaceutica N.V., Beerse, Belgium.

Publikováno v: Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2020 Jan; Vol. 849, pp. 503137. Date of Electronic Publication: 2020 Jan 13.

Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells.

Autor: Sonneveld E; Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht., van den Brink CE, van der Leede BM, Schulkes RK, Petkovich M, van der Burg B, van der Saag PT

Publikováno v: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research [Cell Growth Differ] 1998 Aug; Vol. 9 (8), pp. 629-37.

Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation.

Autor: Kester HA; Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., van der Leede BM, van der Saag PT, van der Burg B

Publikováno v: The Journal of biological chemistry [J Biol Chem] 1997 Jun 27; Vol. 272 (26), pp. 16637-43.

CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids.

Autor: Westin S; Department of Medical Nutrition, Karolinska Institute, Huddinge University Hospital, Novum, Sweden., Sonneveld E, van der Leede BM, van der Saag PT, Gustafsson JA, Mode A

Publikováno v: Molecular and cellular endocrinology [Mol Cell Endocrinol] 1997 May 16; Vol. 129 (2), pp. 169-79.