Impact of bimekizumab and certolizumab pegol on efficacy, safety and osteoblastic activity in radiographic axial spondyloarthritis: results from a phase IIa, multicentre, randomised, double-blind, exploratory study with PET-CT imaging.

Autor: Baraliakos X; Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany., de Jongh J; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Amsterdam UMC, Amsterdam, The Netherlands., Poddubnyy D; Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Epidemiology, German Rheumatism Research Centre, Berlin, Germany., Zwezerijnen GJC; Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, The Netherlands., Hemke R; Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, The Netherlands., Glatt S; UCB, Brussels, Belgium., Shaw S; UCB, Slough, UK., Ionescu L; UCB, Brussels, Belgium., El Baghdady A; UCB, Slough, UK.; Centre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, King's College London, London, UK., Mann J; UCB, Slough, UK., Maguire RP; UCB, Brussels, Belgium., Vaux T; UCB, Slough, UK., de Peyrecave N; UCB, Brussels, Belgium., Oortgiesen M; UCB, Raleigh, NC, USA., Baeten D; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Amsterdam.; UMC, Amsterdam, The Netherlands UCB, Slough, UK., van der Laken C; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Amsterdam UMC, De Boelelaan 1117, 1081 HV Amsterdam, Amsterdam, The Netherlands.

Publikováno v: Therapeutic advances in musculoskeletal disease [Ther Adv Musculoskelet Dis] 2024 Nov 28; Vol. 16, pp. 1759720X241293944. Date of Electronic Publication: 2024 Nov 28 (Print Publication: 2024).

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MACROPHAGE PET/CT IMAGING OF THE FEET CAN CONTRIBUTE TO EARLY PREDICTION OF THERAPY OUTCOME IN RHEUMATOID ARTHRITIS

Autor: Verweij, N. J. F., Ter Wee, M., De Jongh, J., Zwezerijnen, G. C. J., Yaqub, M., Van Schaardenburg, D., Voskuyl, A., Lems, W., Lammertsma, A. A., Boers, M., Van der Laken, C. J.

Publikováno v: Annals of the Rheumatic Diseases, 80, 114-114. BMJ Publishing Group
Verweij, N J F, Ter Wee, M, De Jongh, J, Zwezerijnen, G C J, Yaqub, M, Van Schaardenburg, D, Voskuyl, A, Lems, W, Lammertsma, A A, Boers, M & Van der Laken, C J 2021, ' MACROPHAGE PET/CT IMAGING OF THE FEET CAN CONTRIBUTE TO EARLY PREDICTION OF THERAPY OUTCOME IN RHEUMATOID ARTHRITIS ', Annals of the Rheumatic Diseases, vol. 80, pp. 114-114 . https://doi.org/10.1136/annrheumdis-2021-eular.2189

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5bae223293a7643be3c2d3f20d04a567
https://research.vumc.nl/en/publications/1f2b0404-805f-4798-8ead-b2d344248c39

IS VERY EARLY TREATMENT EFFECTIVE? SIX MONTHS RESULTS OF THE PREVAS STUDY, A PLACEBO-CONTROLLED TRIAL WITH ETANERCEPT IN PATIENTS SUSPECTED OF NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS

Autor: Rusman, T., Van der Weijden, M. A. C., Nurmohamed, M. T., Landewe, R. B. M., De Winter, J. J., Boden, B. J. H., Bet, P. M., Van der Bijl, C. M. A., Van der Laken, C. J., Van der Horst-Bruinsma, I.

Publikováno v: Annals of the Rheumatic Diseases, 79, 72-73. BMJ Publishing Group
Rusman, T, Van der Weijden, M A C, Nurmohamed, M T, Landewe, R B M, De Winter, J J, Boden, B J H, Bet, P M, Van der Bijl, C M A, Van der Laken, C J & Van der Horst-Bruinsma, I 2020, ' IS VERY EARLY TREATMENT EFFECTIVE? SIX MONTHS RESULTS OF THE PREVAS STUDY, A PLACEBO-CONTROLLED TRIAL WITH ETANERCEPT IN PATIENTS SUSPECTED OF NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS ', Annals of the Rheumatic Diseases, vol. 79, pp. 72-73 . https://doi.org/10.1136/annrheumdis-2020-eular.3472

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1614916d71c2bfa2e66900b78edbde22
https://research.vumc.nl/en/publications/643a0947-8394-4826-b9ad-6a94b5fef179

Methotrexate Provokes Disparate Folate Metabolism Gene Expression and Alternative Splicing in Ex Vivo Monocytes and GM-CSF- and M-CSF-Polarized Macrophages.

Autor: Muller IB; Department of Laboratory Medicine, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands., Lin M; Department of Laboratory Medicine, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands., de Jonge R; Department of Laboratory Medicine, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands., Will N; Facility for Environment and Natural Science, Brandenburg Technical University Cottbus-Senftenberg, 01968 Senftenberg, Germany., López-Navarro B; Laboratorio de Inmuno-Metabolismo e Inflamación, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital Gregorio Marañón, 28007 Madrid, Spain., van der Laken C; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center-location VUmc, 1081 HV Amsterdam, The Netherlands., Struys EA; Department of Laboratory Medicine, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands., Oudejans CBM; Department of Laboratory Medicine, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands., Assaraf YG; The Fred Wyszkowski Cancer Research Laboratory, Department of Biology, Technion-Israel Institute of Technology, Haifa 3200003, Israel., Cloos J; Department of Hematology, Amsterdam University Medical Center-location VUmc, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands., Puig-Kröger A; Laboratorio de Inmuno-Metabolismo e Inflamación, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital Gregorio Marañón, 28007 Madrid, Spain., Jansen G; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center-location VUmc, 1081 HV Amsterdam, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 01; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 01.