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Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group.

Autor: van der Kruijssen DEW; Department of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht., Elias SG; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht., van de Ven PM; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht., van Rooijen KL; Department of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht., Lam-Boer J'; Department of Surgery, Radboud University Medical Center, Nijmegen; Department of Surgery, Netherlands Cancer Institute, Amsterdam., Mol L; Clinical Research Department, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht., Punt CJA; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht., Sommeijer DW; Department of Medical Oncology, Amsterdam University Medical Center, Amsterdam; Department of Medical Oncology, Flevo Hospital, Almere., Tanis PJ; Department of Surgery, Amsterdam University Medical Center, Amsterdam; Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands., Nielsen JD; Department of Surgery, Aalborg University Hospital, Aalborg, Denmark., Yilmaz MK; Department of Medical Oncology, Aalborg University Hospital, Aalborg, Denmark., van Riel JMGH; Department of Medical Oncology, Elisabeth-TweeSteden Hospital, Tilburg., Wasowiz-Kemps DK; Department of Surgery, Elisabeth-TweeSteden Hospital, Tilburg., Loosveld OJL; Department of Medical Oncology, Amphia Hospital, Breda., van der Schelling GP; Department of Surgery, Amphia Hospital, Breda., de Groot JWB; Department of Medical Oncology, Isala Hospital, Zwolle, The Netherlands., van Westreenen HL; Department of Surgery, Isala Hospital, Zwolle, The Netherlands., Jakobsen HL; Department of Surgery, Herlev and Gentofte Hospital, Herlev, Denmark., Fromm AL; Department of Medical Oncology, Herlev and Gentofte Hospital, Herlev, Denmark., Hamberg P; Department of Medical Oncology, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands., Verseveld M; Department of Surgery, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands., Jaensch C; Department of Surgery, Regional Hospital Gødstrup, Herning, Denmark., Liposits GI; Department of Medical Oncology, Regional Hospital Gødstrup, Herning, Denmark., van Duijvendijk P; Department of Surgery, Gelre Hospital, Apeldoorn., Oulad Hadj J; Department of Medical Oncology, Gelre Hospital, Apeldoorn., van der Hoeven JAB; Department of Surgery, Albert Schweitzer Hospital, Dordrecht, The Netherlands., Trajkovic M; Department of Medical Oncology, Albert Schweitzer Hospital, Dordrecht, The Netherlands., de Wilt JHW; Department of Surgery, Radboud University Medical Center, Nijmegen., Koopman M; Department of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht. Electronic address: M.Koopman-6@umcutrecht.nl.

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2024 Sep; Vol. 35 (9), pp. 769-779. Date of Electronic Publication: 2024 Jun 07.