Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists

Autor: G. Krivoshein, E. A. Tolner, van den Maagdenberg AMJM, R. A. Giniatullin

Publikováno v: The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-12 (2022)

Abstract Background Migraine is a common brain disorder that predominantly affects women. Migraine pain seems mediated by the activation of mechanosensitive channels in meningeal afferents. Given the role of transient receptor potential melastatin 3

Externí odkaz: https://doaj.org/article/59649d1e58924ebab5b63313af98de9d

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

Autor: Onderwater, GLJ, Ligthart, L, Bot, M, Demirkan, A, Fu, J, Van Der Kallen, CJH, Vijfhuizen, LS, Pool, R, Liu, J, Vanmolkot, FHM, Beekman, M, Wen, K-X, Amin, N, Thesing, CS, Pijpers, JA, Kies, DA, Zielman, R, De Boer, I, Van Greevenbroek, MMJ, Arts, ICW, Milaneschi, Y, Schram, MT, Dagnelie, PC, Franke, L, Ikram, MA, Ferrari, MD, Goeman, JJ, Slagboom, PE, Wijmenga, C, Stehouwer, CDA, Boomsma, DI, Van Duijn, CM, Penninx, BW, Hoen, PAC, Terwindt, GM, Van Den Maagdenberg, AMJM, Consortium, Bbmri Metabolomics

Publikováno v: Neurology, 92(16), E1899-E1911. Lippincott Williams & Wilkins
Neurology, 92(16), E1899-E1911. LIPPINCOTT WILLIAMS & WILKINS
Neurology, 92, 16, pp. e1899-e1911
Neurology, 92(16), E1899-E1911
Neurology, 92(16), e1899-e1911. Lippincott Williams and Wilkins
Neurology
Neurology, 92, e1899-e1911
BBMRI Metabolomics Consortium 2019, ' Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine ', Neurology, vol. 92, no. 16, pp. e1899-e1911 . https://doi.org/10.1212/WNL.0000000000007313
Onderwater, G L J, Ligthart, L, Bot, M, Demirkan, A, Fu, J, van der Kallen, C J H, Vijfhuizen, L S, Pool, R, Liu, J, Vanmolkot, F H M, Beekman, M, Wen, K X, Amin, N, Thesing, C S, Pijpers, J A, Kies, D A, Zielman, R, de Boer, I, van Greevenbroek, M M J, Arts, I C W, Milaneschi, Y, Schram, M T, Dagnelie, P C, Franke, L, Ikram, M A, Ferrari, M D, Goeman, J J, Slagboom, P E, Wijmenga, C, Stehouwer, C D A, Boomsma, D I, van Duijn, C M, Penninx, B W, 't Hoen, P A C, Terwindt, G M, van den Maagdenberg, A M J M & BBMRI Metabolomics Consortium 2019, ' Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine ', Neurology, vol. 92, no. 16, pp. e1899-e1911 . https://doi.org/10.1212/WNL.0000000000007313
Neurology, 92(16), e1899-e1911. American Academy of Neurology

ObjectiveTo identify a plasma metabolomic biomarker signature for migraine.MethodsPlasma samples from 8 Dutch cohorts (n = 10,153: 2,800 migraine patients and 7,353 controls) were profiled on a 1H-NMR-based metabolomics platform, to quantify 146 indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9478ab4f619b8b6edc5ef010bd23a1fb
https://pure.eur.nl/en/publications/cc493bdc-b960-4c5a-a720-12c94e46d62a

Shared genetic basis for migraine and ischemic stroke

Autor: Malik, R, Freilinger, T, Winsvold, BS, Anttila, V, Vander Heiden, J, Traylor, M, De Vries, B, Holliday, EG, Terwindt, GM, Sturm, J, Bis, JC, Hopewell, JC, Ferrari, MD, Rannikmae, K, Wessman, M, Kallela, M, Kubisch, C, Fornage, M, Meschia, JF, Lehtimäki, T, Sudlow, C, Clarke, R, Chasman, DI, Mitchell, BD, Maguire, J, Kaprio, J, Farrall, M, Raitakari, OT, Kurth, T, Ikram, MA, Reiner, AP, Longstreth, WT, Rothwell, PM, Strachan, DP, Sharma, P, Seshadri, S, Quaye, L, Cherkas, L, Schürks, M, Rosand, J, Ligthart, L, Boncoraglio, GB, Davey Smith, G, Van Duijn, CM, Stefansson, K, Worrall, BB, Nyholt, DR, Markus, HS, Van Den Maagdenberg, AMJM, Cotsapas, C, Zwart, JA, Palotie, A, Dichgans, M

© 2015 American Academy of Neurology. Objective: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to common genetic variation. Methods: We applied 4 different approaches to large-scale meta-analyses of genome-wide d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e4f111e7016ed4524502241562f8d86f
https://europepmc.org/articles/pmc4451048

Familial partial epilepsy with variable foci in a Dutch family: clinical characteristics and confirmation of linkage to chromosome 22q

Autor: Callenbach, PMC, van den Maagdenberg, AMJM, Hottenga, JJ, van den Boogerd, EH, de Coo, RFM, Lindhout, D, Frants, RR, Sandkuijl, LA, Brouwer, OF

Publikováno v: Epilepsia, 44, 1298-1305. Wiley-Blackwell Publishing Ltd
Epilepsia, 44(10), 1298-1305. Wiley

Purpose: Three forms of idiopathic partial epilepsy with autosomal dominant inheritance have been described: (a) autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE); (b) autosomal dominant lateral temporal epilepsy (ADLTE) or partial epilepsy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a6fe7d51627a1a2aaa0cc0365f3cb623
https://pure.eur.nl/en/publications/23b29fff-5b0a-455e-b395-73cd2a54e8e1

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